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Diarylpropionitrile
CAS No. 1428-67-7
Diarylpropionitrile ( DPN )
产品货号. M11807 CAS No. 1428-67-7
Diarylpropionitrile (DPN) is a non-steroidal estrogen receptor β(ERβ) selective ligand.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥259 | 有现货 |
|
| 10MG | ￥421 | 有现货 |
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| 25MG | ￥875 | 有现货 |
|
| 50MG | ￥1604 | 有现货 |
|
| 100MG | ￥2851 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Diarylpropionitrile
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Diarylpropionitrile (DPN) is a non-steroidal estrogen receptor β(ERβ) selective ligand.
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产品描述Diarylpropionitrile (DPN) is a non-steroidal estrogen receptor β(ERβ) selective ligand, demonstrates the neuroprotective effects against 10 0M Aβ1-42-induced oxidative stress and inflammation in primary rat cortical cell culture; (1-100 nM) significantly decreases neuronal cell death by increasing cell viability through a significant attenuation in the reactive oxygen species level, downregulation of pro-apoptotic activated caspase-3 and Bax, and upregulation of anti-apoptotic Bcl-2; decreases the expression levels of IL-1β and IL-6; inhibits medulloblastoma development via anti-proliferative and pro-apototic pathways.
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同义词DPN
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通路Endocrinology/Hormones
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靶点Estrogen Receptor/ERR
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受体Estrogen Receptor/ERR
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研究领域Neurological Disease
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适应症——
化学信息
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CAS Number1428-67-7
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分子量239.27
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分子式C15H13NO2
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纯度>98% (HPLC)
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溶解度10 mM in DMSO
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SMILESC1=CC(=CC=C1CC(C#N)C2=CC=C(C=C2)O)O
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化学全称Benzenepropanenitrile, 4-hydroxy-α-(4-hydroxyphenyl)-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
2. Khalaj AJ, et al. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):19125-30.
3. Mancuso M, et al. Cancer Lett. 2011 Sep 28;308(2):197-202.
4. Motylewska E, et al. Cancer Lett. 2009 Apr 8;276(1):68-73.
产品手册
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