021-51111890
购物车（）
sales@molnova.cn
GR-127935
CAS No. 148672-13-3
GR-127935 ( GR127935 )
产品货号. M12051 CAS No. 148672-13-3
GR-127935 is a potent and selective 5-HT1B/1D receptor antagonist with pKi of 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptor.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥10287 | 有现货 |
|
| 50MG | ￥20898 | 有现货 |
|
| 100MG | ￥27540 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称GR-127935
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述GR-127935 is a potent and selective 5-HT1B/1D receptor antagonist with pKi of 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptor.
-
产品描述GR-127935 is a potent and selective 5-HT1B/1D receptor antagonist with pKi of 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptor; displays >100-fold selectivity over 5HT1A, 5-HT2A, 5-HT2C receptors and other receptor types; blocks porcine carotid vascular response to sumatriptan in vivo; orally bioavailable and centrally active.
-
同义词GR127935
-
通路Endocrinology/Hormones
-
靶点5-HT Receptor
-
受体5-HT Receptor
-
研究领域——
-
适应症——
化学信息
-
CAS Number148672-13-3
-
分子量497.59
-
分子式C29H31N5O3
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESCC1=C(C=CC(=C1)C2=NOC(=N2)C)C3=CC=C(C=C3)C(=O)NC4=CC(=C(C=C4)OC)N5CCN(CC5)C
-
化学全称N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]-4-[2-methyl-4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]benzamide
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Clitherow JW, et al. J Med Chem. 1994 Jul 22;37(15):2253-7.
2. Knobelman DA, et al. J Pharmacol Exp Ther. 2001 Sep;298(3):1083-91.
3. De Vries P, et al. Br J Pharmacol. 1996 May;118(1):85-92.
2. Knobelman DA, et al. J Pharmacol Exp Ther. 2001 Sep;298(3):1083-91.
3. De Vries P, et al. Br J Pharmacol. 1996 May;118(1):85-92.
产品手册
关联产品
-
Ataractan
Azacyclonol, also known as γ-pipradol, is a drug used to diminish hallucinations in psychotic individuals.
-
PF-05212377
PF-05212377 (SAM-760, PF 5212377) is a potent and selective 5-HT6 receptor antagonist with potential therapy for the symptomatic treatment of mild to moderate Alzheimer's disease.
-
Lurasidone hydrochlo...
Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma.
