Pardoprunox ( —— )

产品货号. M13825 CAS No. 269718-84-5

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产品名称

Pardoprunox
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Pardoprunox(SLV-308) is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist.
产品描述

Pardoprunox(SLV-308) is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist; D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist (IA = 50% and 67%, respectively) and 5-HT1A receptor (pKi = 8.5) full agonist (IA = 100%); also binds to D4 (pKi = 7.8), α1-adrenergic (pKi = 7.8), α2-adrenergic (pKi = 7.4), and 5-HT7 receptors (pKi = 7.2) with lower affinity.
同义词

——
通路

Endocrinology/Hormones
靶点

5-HT Receptor
受体

5-HT1A; α2-adrenergic receptor; D2; D3
研究领域

Neurological Disease
适应症

——

1.Glennon JC, et al. Synapse. 2006 Dec 15;60(8):599-608.

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