Enoxolone ( Arthrodont; Biosone; Enoxolone; α-Glycyrrhetinic Acid; GM 1658; NSC 35347; PO 12; STX 352 )

产品货号. M14567 CAS No. 471-53-4

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Enoxolone
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Enoximone is a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity that does not cause changes in myocardial oxygen consumption.
产品描述

Enoximone is a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity that does not cause changes in myocardial oxygen consumption. It is used in patients with congestive heart failure. Trials were halted in the U.S., but the drug is used in various countries.
同义词

Arthrodont; Biosone; Enoxolone; α-Glycyrrhetinic Acid; GM 1658; NSC 35347; PO 12; STX 352
通路

Metabolic Enzyme/Protease
靶点

Dehydrogenase
受体

DHO
研究领域

Other Indications
适应症

——

CAS Number

471-53-4
分子量

470.68
分子式

C30H46O4
纯度

>98%(HPLC)
溶解度

DMSO: 94 mg/mL (199.71 mM)
SMILES

CC(C)([C@](CC[C@@]([C@@]1(CC[C@]2(CC[C@](C(O)=O)(C[C@]2(C1=C3)[H])C)C)C)4C)5[H])[C@@H](O)CC[C@]5(C)[C@@]4([H])C3=O
化学全称

(2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicene-2-carboxylic acid

1.Boldt J, et al. Expert Opin PharmacOthers. 2007, 8(13):2135-47.

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