Clozapine ( HF 1854 )

产品货号. M15120 CAS No. 5786-21-0

An atypical antipsychotic agent that binds to 5-HT and dopamine receptor; is also potent at the α2-adrenoceptor with Ki of 51 nM.

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
50MG	￥518	有现货
100MG	￥786	有现货
200MG	￥1401	有现货
500MG	￥2576	有现货
1G	￥3831	有现货

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生物学信息

产品名称

Clozapine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

An atypical antipsychotic agent that binds to 5-HT and dopamine receptor; is also potent at the α2-adrenoceptor with Ki of 51 nM.
产品描述

An atypical antipsychotic agent that binds to 5-HT and dopamine receptor; is also potent at the α2-adrenoceptor with Ki of 51 nM; mainly used for schizophrenia.Schizophrenia Approved
同义词

HF 1854
通路

GPCR/G Protein
靶点

Dopamine Receptor
受体

D2;M1mAChR;α2-adrenoceptor
研究领域

Neurological Disease
适应症

Schizophrenia

化学信息

CAS Number

5786-21-0
分子量

326.82
分子式

C18H19ClN4
纯度

>98% (HPLC)
溶解度

10 mM in DMSO
SMILES

CN1CCN(CC1)C2=C3C=CC=CC3=NC4=C(N2)C=C(C=C4)Cl
化学全称

5H-Dibenzo[b,e][1,4]diazepine, 8-chloro-11-(4-methyl-1-piperazinyl)-

运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1. Seeman P, et al. ACS Chem Neurosci. 2014 Jan 15;5(1):24-9.
2. Zhukovskaya NL, et al. Neurosci Lett. 2000 Jul 21;288(3):236-40.
3. Moreno JL, et al. Psychopharmacology (Berl). 2013 Jan;225(1):217-26.

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