Camalexin ( —— )

产品货号. M22164 CAS No. 135531-86-1

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产品名称

Camalexin
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Camalexin is a phytoalexin isolated from Camelina sativa. It has antifungal, antibacterial, antiproliferative, and anticancer activities.
产品描述

Camalexin is a phytoalexin isolated from Camelina sativa. It has antifungal, antibacterial, antiproliferative, and anticancer activities. Camalexin can induce ROS production.Camalexin shows antiproliferative activity against a human breast cancer cell line. For the oomycetes, Phytophthora and Pythium Nep1-like proteins are the initial triggers of Camalexin synthesis and formation of ROS. ROS appear to be of general relevance for Camalexin formation. In a screen for enhanced susceptibility to Alternaria brassicicola the esa1 mutant is identified, which shows delayed Camalexin induction. Particularly in response to ROS inducing agents reduced Camalexin levels are synthesized. This crucial role for ESA1 is confirmed by the inability of esa1 mutants to synthesize Camalexin in response to Leptosphaeria maculans.
同义词

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通路

Immunology/Inflammation
靶点

ROS
受体

ROS
研究领域

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适应症

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1. William A.Ayer, et al. Synthesis of camalexin and related phytoalexins. Tetrahedron. Volume 48, Issue 14, 1992, Pages 2919-2924.

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