CFI02 ( CFI 02;CFI-02 )

产品货号. M13838 CAS No. 273735-28-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

CFI02
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

CFI02 (CFI-02) is a specific inhibitor of human cytomegalovirus (HCMV) glycoprotein B-mediated fusion with IC50 of 40 nM against laboratory adapted HCMV strain AD169.
产品描述

CFI02 (CFI-02) is a specific inhibitor of human cytomegalovirus (HCMV) glycoprotein B-mediated fusion with IC50 of 40 nM against laboratory adapted HCMV strain AD169; reduces HCMV yield by >3 logs at 1 uM, and shows no inhibitory activity against closely related betaherpesviruses (including MCMV, simian CMV, and RCMV) (IC50>20 uM) as well as cytotoxic effect (CC50>50 uM).
同义词

CFI 02;CFI-02
通路

Microbiology/Virology
靶点

CMV
受体

CMV
研究领域

——
适应症

——

CAS Number

273735-28-7
分子量

491.43
分子式

C18H11F6N5OS2
纯度

>98% (HPLC)
溶解度

——
SMILES

——
化学全称

N-(4-(3-(3,5-bis(trifluoromethyl)phenyl)thioureido)phenyl)-1,2,3-thiadiazole-4-carboxamide

1. Jones TR, et al. J Virol. 2004 Feb;78(3):1289-300.
2. Bloom JD, et al. Bioorg Med Chem Lett. 2003 Sep 1;13(17):2929-32.

计算器

产品手册

关联产品

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CEF20, a CEF control peptide pool, is an HLA-A*0201-restricted epitope from cytomegalovirus pp65 (495-503).
BDCRB

BDCRB (GW 275175) is a potent and selective inhibitor of human CMV replication by blocking the processing and maturation of viral DNA.
CFI02

CFI02 (CFI-02) is a specific inhibitor of human cytomegalovirus (HCMV) glycoprotein B-mediated fusion with IC50 of 40 nM against laboratory adapted HCMV strain AD169.