AVN-211 ( AVN211;CD-008-0173 )

产品货号. M10580 CAS No. 1173103-84-8

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产品名称

AVN-211
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

AVN-211 (CD-008-0173) is a novel and highly selective 5-HT6 receptor small molecule antagonist with Ki of 2.34 nM.
产品描述

AVN-211 (CD-008-0173) is a novel and highly selective 5-HT6 receptor small molecule antagonist with Ki of 2.34 nM; shows a similar or better anxiolytic efficacy than fenobam, rufinamide, lorazepam, and buspirone in an elevated plus-maze model; significantly delayes or partially halts the progressive decline in memory function associated with AD.Schizophrenia Phase 3 Clinical
同义词

AVN211;CD-008-0173
通路

Endocrinology/Hormones
靶点

5-HT Receptor
受体

5-HT Receptor
研究领域

Neurological Disease
适应症

Schizophrenia

1. Ivachtchenko AV, et al. Mol Pharm. 2016 Mar 7;13(3):945-63.
2. Morozova MA,et al. CNS Spectr. 2014 Aug;19(4):316-23.

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