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8-Prenylnaringenin

CAS No. 53846-50-7

8-Prenylnaringenin ( —— )

产品货号. M22019 CAS No. 53846-50-7

8-Prenylnaringenin is a phytoestrogen with high estrogenic activity,In vitro, aggregates of buccal epithelial cells were irradiated and cultured in suspension for 11 days.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥3726 有现货
10MG ¥5476 有现货
25MG ¥8586 有现货
50MG ¥11583 有现货
100MG ¥15633 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    8-Prenylnaringenin
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    8-Prenylnaringenin is a phytoestrogen with high estrogenic activity,In vitro, aggregates of buccal epithelial cells were irradiated and cultured in suspension for 11 days.
  • 产品描述
    8-Prenylnaringenin is a phytoestrogen with high estrogenic activity,In vitro, aggregates of buccal epithelial cells were irradiated and cultured in suspension for 11 days. 8-PN or TAM were investigated regarding their effect on cell shedding. In vivo, the lower tongue surface of mice was irradiated with graded single doses of 25 kV X-rays. The incidence, latency, and duration of the resulting mucosal ulcerations were analyzed after topical treatment with 8-PN, TAM or solvent. 8-PN or TAM prevented the volume reduction of the irradiated cell aggregates during the incubation period. This was the result of a higher residual cell number in the treated versus the untreated irradiated aggregates. In vivo, topical treatment with 8-PN or TAM significantly increased the latency of mucositis from 10.9 to 12.1 and 12.4 days respectively, while the ulcer incidence was unchanged.
  • 同义词
    ——
  • 通路
    Immunology/Inflammation
  • 靶点
    ROS
  • 受体
    ROS
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    53846-50-7
  • 分子量
    340.38
  • 分子式
    C20H20O5
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    CC(C)=CCC1=C2O[C@@H](CC(=O)C2=C(O)C=C1O)C1=CC=C(O)C=C1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.8-prenylnaringenin and tamoxifen inhibit the shedding of irradiated epithelial cells and increase the latency period of radiation-induced oral mucositis : cell culture and murine model.Strahlenther Onkol. 2015 May;191(5):429-36.
产品手册
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  • 8-Prenylnaringenin

    8-Prenylnaringenin is a phytoestrogen with high estrogenic activity,In vitro, aggregates of buccal epithelial cells were irradiated and cultured in suspension for 11 days.