25CN-NBOH
CAS No. 1391489-32-9
25CN-NBOH ( 25CN NBOH )
产品货号. M11623 CAS No. 1391489-32-9
A potent, highly selective and brain-penetrant 5-HT2A receptor agonist with Ki of 1.1 nM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
100MG | 获取报价 | 有现货 |
|
200MG | 获取报价 | 有现货 |
|
500MG | 获取报价 | 有现货 |
|
1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称25CN-NBOH
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述A potent, highly selective and brain-penetrant 5-HT2A receptor agonist with Ki of 1.1 nM.
-
产品描述A potent, highly selective and brain-penetrant 5-HT2A receptor agonist with Ki of 1.1 nM ([3H]ketanserin); >100-fold over 5-HT2CR and 46-fold selectivity over 5-HT2BR; exhibits 30- to 180-fold 5-HT2A/5-HT2C selectivities and 54-fold 5-HT2A/5-HT2B selectivity in inositol phosphate and intracellular Ca2+ mobilization assays; is a superior selective and brain-penetrant 5-HT2A receptor agonist compared with (±)-2,5-dimethoxy-4-iodoamphetamine (DOI).
-
同义词25CN NBOH
-
通路Endocrinology/Hormones
-
靶点5-HT Receptor
-
受体5-HT Receptor
-
研究领域——
-
适应症——
化学信息
-
CAS Number1391489-32-9
-
分子量312.37
-
分子式C18H20N2O3
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESCOC1=CC(=C(C=C1CCNCC2=CC=CC=C2O)OC)C#N.Cl
-
化学全称2-([2-(4-cyano-2,5-dimethoxyphenyl) ethylamino]methyl)phenol
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Jensen AA, et al. J Pharmacol Exp Ther. 2017 Jun;361(3):441-453.
2. Fantegrossi WE, et al. Psychopharmacology (Berl). 2015 Mar;232(6):1039-47.
3. Halberstadt AL, et al. Neuropharmacology. 2016 Aug;107:364-375.
4. Hansen M, et al. ACS Chem Neurosci. 2014 Mar 19;5(3):243-9.
2. Fantegrossi WE, et al. Psychopharmacology (Berl). 2015 Mar;232(6):1039-47.
3. Halberstadt AL, et al. Neuropharmacology. 2016 Aug;107:364-375.
4. Hansen M, et al. ACS Chem Neurosci. 2014 Mar 19;5(3):243-9.
产品手册
关联产品
-
Zacopride hydrochlor...
Zacopride is a highly potent 5-HT3 receptor antagonist (Kd = 0.38 nM) and 5-HT4 receptor agonist (Ki = 373 nM). It also is a selective IK1 channel agonist.
-
Alverine citrate
Alverine Citrate(NSC35459) is a drug used for functional gastrointestinal disorders.
-
Duloxetine hydrochlo...
Duloxetine hydrochloride is a selective serotonin and norepinephrine reuptake inhibitor .