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25CN-NBOH

CAS No. 1391489-32-9

25CN-NBOH ( 25CN NBOH )

产品货号. M11623 CAS No. 1391489-32-9

A potent, highly selective and brain-penetrant 5-HT2A receptor agonist with Ki of 1.1 nM.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    25CN-NBOH
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A potent, highly selective and brain-penetrant 5-HT2A receptor agonist with Ki of 1.1 nM.
  • 产品描述
    A potent, highly selective and brain-penetrant 5-HT2A receptor agonist with Ki of 1.1 nM ([3H]ketanserin); >100-fold over 5-HT2CR and 46-fold selectivity over 5-HT2BR; exhibits 30- to 180-fold 5-HT2A/5-HT2C selectivities and 54-fold 5-HT2A/5-HT2B selectivity in inositol phosphate and intracellular Ca2+ mobilization assays; is a superior selective and brain-penetrant 5-HT2A receptor agonist compared with (±)-2,5-dimethoxy-4-iodoamphetamine (DOI).
  • 同义词
    25CN NBOH
  • 通路
    Endocrinology/Hormones
  • 靶点
    5-HT Receptor
  • 受体
    5-HT Receptor
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1391489-32-9
  • 分子量
    312.37
  • 分子式
    C18H20N2O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    COC1=CC(=C(C=C1CCNCC2=CC=CC=C2O)OC)C#N.Cl
  • 化学全称
    2-([2-(4-cyano-2,5-dimethoxyphenyl) ethylamino]methyl)phenol

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Jensen AA, et al. J Pharmacol Exp Ther. 2017 Jun;361(3):441-453.
2. Fantegrossi WE, et al. Psychopharmacology (Berl). 2015 Mar;232(6):1039-47.
3. Halberstadt AL, et al. Neuropharmacology. 2016 Aug;107:364-375.
4. Hansen M, et al. ACS Chem Neurosci. 2014 Mar 19;5(3):243-9.
产品手册
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