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(Z)-4-Hydroxytamoxifen
CAS No. 68047-06-3
(Z)-4-Hydroxytamoxifen ( trans-4-Hydroxytamoxifen )
产品货号. M15596 CAS No. 68047-06-3
A major metabolite of tamoxifen, a well-known Estrogen receptor antagonist in breast but partial estrogen receptor agonist in endometrium.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥518 | 有现货 |
|
| 10MG | ￥721 | 有现货 |
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| 25MG | ￥1596 | 有现货 |
|
| 50MG | ￥3127 | 有现货 |
|
| 100MG | ￥4609 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称(Z)-4-Hydroxytamoxifen
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A major metabolite of tamoxifen, a well-known Estrogen receptor antagonist in breast but partial estrogen receptor agonist in endometrium.
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产品描述A major metabolite of tamoxifen, a well-known Estrogen receptor antagonist in breast but partial estrogen receptor agonist in endometrium; shows a 100-fold increased affinity for ER and approximately 100-times more potent than trans-tamoxifen in suppressing cell growth and plasminogen activator activity.
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同义词trans-4-Hydroxytamoxifen
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通路Endocrinology/Hormones
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靶点Estrogen Receptor/ERR
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受体ER
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研究领域Cancer
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适应症——
化学信息
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CAS Number68047-06-3
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分子量387.51
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分子式C26H29NO2
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纯度>98% (HPLC)
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溶解度DMSO: ≥ 28 mg/mL
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SMILESOC1=CC=C(/C(C2=CC=C(OCCN(C)C)C=C2)=C(C3=CC=CC=C3)\CC)C=C1
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化学全称Phenol, 4-[(1Z)-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Katzenellenbogen BS, et al. Cancer Res. 1984 Jan;44(1):112-9.
2. Desta Z, et al. J Pharmacol Exp Ther. 2004 Sep;310(3):1062-75.
3. Crewe HK, et al. Drug Metab Dispos. 2002 Aug;30(8):869-74.
2. Desta Z, et al. J Pharmacol Exp Ther. 2004 Sep;310(3):1062-75.
3. Crewe HK, et al. Drug Metab Dispos. 2002 Aug;30(8):869-74.
产品手册
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