Terpenoids
Terpenes consist of a group of 30,000 reported chemicals, and have been known as constituents of flavors, antifeedants and pheromones. Terpenes are made from the isoprene unit (C5), and, according to the number of units, they are classified as hemi- (C5), mono- (C10), sesqui- (C15), di- (C20), sester- (C25), tri- (C30), tetra- (C40), or polyterpenes ((C5)n; n > 8). A number of modification products and derivatives, collectively referred to as terpenoids, have also been characterized, and include steroids/sterols, saponins and meroterpenes. Terpenes have also been reported to be beneficial for human health due to their anti-inflammation, anti-carcinogenesis and neuroprotection effects. Furthermore, the involvement of specific cell signaling pathways, such as mitogen-activated protein kinase (MAPK), nuclear factor κ-light-chain-enhancer of activated B cells (NF-κB), and c-Jun N-terminal kinase (JNK), as well as the production of cytokines, such as interleukin 6 (IL-6) and tumor necrosis factor α (TNF-α), have been found to be responsible for these effects. Such biological activity is often related with specific sub-groups of terpenes such as cannabinoids, retinoids, steroids, taxanes and terpenoid indole alkaloids. Although terpenes are known as activators and inhibitors for enzymes and signal mediators, estrogenic terpenes and terpenoids comprise an important phytoestrogen class due to their contribution to or influence on human health.
References
1.Kiyama R. Eur J Pharmacol. 2017;815:405–415.
References
1.Kiyama R. Eur J Pharmacol. 2017;815:405–415.
Natural Products
Terpenoids
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Isoescin IB
产品货号 : M21793
cas no: 219944-46-4
异七叶皂苷 IB(Isoescin IB)是从七叶树种子中分离出来的,是七叶皂苷 IB 的异构体。异七叶皂苷IB和七叶皂苷IB是七叶皂苷的主要活性成分。 -
Escin IB
产品货号 : M21789
cas no: 26339-90-2
Escin IB 是从七叶树 (Aesculus hippocastanum) 的皮肤和种子胚乳中分离出来的皂苷。 -
31-Norlanostenol
产品货号 : M21735
cas no: 16910-39-7
31-Norlanostenol 是从大戟 (Euphorbia officinarum) 乳胶中分离出来的三萜化合物。 -
Oridonin
产品货号 : M13888
cas no: 28957-04-2
冬凌草甲素是一种活性二萜化合物,具有多种药理活性,包括抗氧化、抗肿瘤和抗炎等。