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sbp-7455
CAS No. 1884222-74-5
sbp-7455 ( —— )
产品货号. M23859 CAS No. 1884222-74-5
SBP-7455 potently inhibited ULK1/2 enzymatic activity in vitro and in cells, reduced the viability of TNBC cells and had oral bioavailability in mice.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥980 | 有现货 |
|
| 10MG | ￥1636 | 有现货 |
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| 25MG | ￥2948 | 有现货 |
|
| 50MG | ￥4811 | 有现货 |
|
| 100MG | ￥6035 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称sbp-7455
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述SBP-7455 potently inhibited ULK1/2 enzymatic activity in vitro and in cells, reduced the viability of TNBC cells and had oral bioavailability in mice.
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产品描述SBP-7455 potently inhibited ULK1/2 enzymatic activity in vitro and in cells, reduced the viability of TNBC cells and had oral bioavailability in mice.
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同义词——
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通路Autophagy
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靶点Autophagy
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受体ULK1;ULK2
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研究领域——
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适应症——
化学信息
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CAS Number1884222-74-5
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分子量354.3
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分子式C16H17F3N4O2
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纯度>98% (HPLC)
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溶解度DMSO:120mg/mL (338.67 mM)
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SMILESCOC1=C(OC)C=CC(NC2=NC(NC3CC3)=C(C(F)(F)F)C=N2)=C1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Ren H, Bakas NA, Vamos M, et al. Design, Synthesis, and Characterization of an Orally Active Dual-Specific ULK1/2 Autophagy Inhibitor that Synergizes with the PARP Inhibitor Olaparib for the Treatment of Triple-Negative Breast Cancer. J Med Chem. 2020;63(23):14609-14625. doi:10.1021/acs.jmedchem.0c00873
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