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pocapavir
CAS No. 146949-21-5
pocapavir ( SCH-48973; SCH48973; SCH 48973; V074 )
产品货号. M17315 CAS No. 146949-21-5
Pocapavir is an investigational enterovirus (EV) capsid inhibitor.
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥356 | 有现货 |
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| 5MG | ￥583 | 有现货 |
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| 10MG | ￥915 | 有现货 |
|
| 25MG | ￥1725 | 有现货 |
|
| 50MG | ￥3013 | 有现货 |
|
| 100MG | ￥4836 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称pocapavir
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Pocapavir is an investigational enterovirus (EV) capsid inhibitor.
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产品描述Pocapavir, also known as SCH-48973 and V-073, is a potent, selective, antienterovirus agent. SCH-48973 had antiviral activity (50% inhibitory concentrations [IC50s]) of 0.02 to 0.11 microg/ml, with no detectable cytotoxicity at 50 microg/ml. SCH-48973 inhibited 80% of 154 recent human enterovirus isolates at an IC50 of 0.9 microg/ml. The affinity constant (Ki) for SCH-48973 binding to poliovirus was 8.85 x 10(-8) M. SCH-48973 demonstrated efficacy in a murine poliovirus model of enterovirus disease. SCH-48973 represents a potential candidate for therapeutic intervention against enterovirus infections.
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同义词SCH-48973; SCH48973; SCH 48973; V074
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通路Autophagy
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靶点Autophagy
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受体Antiviral
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研究领域——
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适应症——
化学信息
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CAS Number146949-21-5
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分子量423.72
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分子式C21H17Cl3O3
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纯度98%
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溶解度DMSO : 100 mg/mL. 236.00 mM; H2O : < 0.1 mg/mL
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SMILESCOc1ccc(OCc2ccc(COc3c(Cl)cccc3Cl)cc2)c(Cl)c1
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化学全称1,3-dichloro-2-((4-((2-chloro-4-methoxyphenoxy)methyl)benzyl)oxy)benzene
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Collett MS, et al. Antiviral Activity of Pocapavir in a Randomized, Blinded, Placebo-Controlled Human Oral Poliovirus Vaccine Challenge Model. J Infect Dis. 2017 Feb 1;215(3):335-343.
产品手册
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