021-51111890
购物车（）
sales@molnova.cn
Talarozole
CAS No. 201410-53-9
Talarozole ( R115866 )
产品货号. M20727 CAS No. 201410-53-9
Talarozole is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥786 | 有现货 |
|
| 5MG | ￥1110 | 有现货 |
|
| 10MG | ￥1434 | 有现货 |
|
| 25MG | ￥2317 | 有现货 |
|
| 50MG | ￥3183 | 有现货 |
|
| 100MG | ￥4739 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Talarozole
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述Talarozole is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA).
-
产品描述Talarozole is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA). Talarozole inhibits both CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM respectively.Talarozole for the treatment of acne psoriasis and other keratinization disorders.
-
同义词R115866
-
通路Autophagy
-
靶点Autophagy
-
受体RAMBA;CYP
-
研究领域Infection
-
适应症Acne; Psoriasis
化学信息
-
CAS Number201410-53-9
-
分子量377.51
-
分子式C21H23N5S
-
纯度>98% (HPLC)
-
溶解度DMSO:36 mg/mL (95.36 mM)
-
SMILESCCC(CC)C(c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Elizabeth Pavez Loriè Chamcheu J C Vahlquist A et al. Both all-trans retinoic acid and cytochrome P450 (CYP26) inhibitors affect the expression of vitamin A metabolizing enzymes and retinoid biomarkers in organotypic epidermis[J]. Archives of Dermatological Research 2009 301(7):475-485.
产品手册
关联产品
-
Glycycoumarin
Glycycoumarin is an estrogen agonist, it shows moderate inhibitory effects against CYP1A2 and CYP2B6.
-
SR-3677
SR-3677 is an effective and specific inhibitor of ROCK2 (IC50: 3 nM).
-
SP-8356
SP-8356 is a potent, orally active inhibitor of cluster of differentiation 147 (CD147) with anti-atherosclerotic effects.
