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Talarozole

CAS No. 201410-53-9

Talarozole ( R115866 )

产品货号. M20727 CAS No. 201410-53-9

Talarozole is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥786 有现货
5MG ¥1110 有现货
10MG ¥1434 有现货
25MG ¥2317 有现货
50MG ¥3183 有现货
100MG ¥4739 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Talarozole
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Talarozole is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA).
  • 产品描述
    Talarozole is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA). Talarozole inhibits both CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46 nM respectively.Talarozole for the treatment of acne psoriasis and other keratinization disorders.
  • 同义词
    R115866
  • 通路
    Autophagy
  • 靶点
    Autophagy
  • 受体
    RAMBA;CYP
  • 研究领域
    Infection
  • 适应症
    Acne; Psoriasis

化学信息

  • CAS Number
    201410-53-9
  • 分子量
    377.51
  • 分子式
    C21H23N5S
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:36 mg/mL (95.36 mM)
  • SMILES
    CCC(CC)C(c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Elizabeth Pavez Loriè Chamcheu J C Vahlquist A et al. Both all-trans retinoic acid and cytochrome P450 (CYP26) inhibitors affect the expression of vitamin A metabolizing enzymes and retinoid biomarkers in organotypic epidermis[J]. Archives of Dermatological Research 2009 301(7):475-485.
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