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首页- Products - Others - Other Targets - p-Cresol

p-Cresol

CAS No. 106-44-5

p-Cresol ( 4-Cresol;4-Methylphenol;4-Hydroxytoluene )

产品货号. M20004 CAS No. 106-44-5

p-Cresol (4-methylphenol) is a partially lipophilic moiety which strongly binds to plasma protein (close to 100%) under normal conditions. p-Cresol is metabolized through conjugation mainly sulphation and glucuronization but removal of the unconjugated p-cresol is at least in part via the urine.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货
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生物学信息

  • 产品名称
    p-Cresol
  • 注意事项
    本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
  • 产品简述
    p-Cresol (4-methylphenol) is a partially lipophilic moiety which strongly binds to plasma protein (close to 100%) under normal conditions. p-Cresol is metabolized through conjugation mainly sulphation and glucuronization but removal of the unconjugated p-cresol is at least in part via the urine.
  • 产品描述
    p-Cresol (4-methylphenol) is a partially lipophilic moiety which strongly binds to plasma protein (close to 100%) under normal conditions. p-Cresol is metabolized through conjugation mainly sulphation and glucuronization but removal of the unconjugated p-cresol is at least in part via the urine. Therefore it is not surprising that this compound together with several other phenoles is retained when the kidneys fail. P-Cresol is an end-product of protein breakdown and an increase of the nutritional protein load in healthy individuals results in enhanced generation and urinary excretion. The serum p-cresol concentration in uremic patients can be decreased by changing to a low-protein diet. p-Cresol is one of the metabolites of the amino acid tyrosine and to a certain extent also of phenylalanine which are converted to 4-hydroxyphenylacetic acid by intestinal bacteria before being decarboxylated to p-cresol (putrefaction).
  • 同义词
    4-Cresol;4-Methylphenol;4-Hydroxytoluene
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    106-44-5
  • 分子量
    108.14
  • 分子式
    C7H8O
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:10 mM
  • SMILES
    Cc1ccc(O)cc1
  • 化学全称
    p-Cresol

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Brunet P et al. Protein-bound uremic retention solutes. Adv Ren Replace Ther. 2003 Oct;10(4):310-20.
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