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alpha-Tocopherolquinone

CAS No. 7559-04-8

alpha-Tocopherolquinone ( A-0001; EPI-A-0001; Vitamin E Quinone (D-form) )

产品货号. M17740 CAS No. 7559-04-8

During hypoxia in rats, levels of α-tocopherylquinon have been found to rise. It is reported to downregulate the respiratory activity of mitochondria.

纯度: 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
10MG ¥243 有现货
25MG ¥518 有现货
50MG ¥753 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    alpha-Tocopherolquinone
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    During hypoxia in rats, levels of α-tocopherylquinon have been found to rise. It is reported to downregulate the respiratory activity of mitochondria.
  • 产品描述
    ɑ-Tocopherolquinone, also known as Vitamin E Quinone (D-form), is a mitochondrial membrane transport protein that has been in phase II clinical trials for the treatment of inherited mitochondrial respiratory chain diseases, however this research has been discontinued. It has also been used for the treatment of Frederich's ataxia and MEILAS syndrome.
  • 同义词
    A-0001; EPI-A-0001; Vitamin E Quinone (D-form)
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    7559-04-8
  • 分子量
    446.71
  • 分子式
    C29H50O3
  • 纯度
    98%
  • 溶解度
    ——
  • SMILES
    CC1=C(C(=O)C(=C(C1=O)C)CC[C@@](C)(CCC[C@H](C)CCC[C@H](C)CCCC(C)C)O)C
  • 化学全称
    ɑ-2-(3-Hydroxy-3,7,11,15-tetramethylhexadecyl)-3,5,6-trimethyl-p-benzoquinone

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Siegel D, et al. The Reduction of α-Tocopherolquinone by Human NAD(P)H:Quinone Oxidoreductase: The Role of α-Tocopherolhydroquinone as a Cellular Antioxidant[J]. Molecular Pharmacology, 1997, 52(2):300-305.
产品手册
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