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Zuclopenthixol

CAS No. 53772-83-1

Zuclopenthixol ( alpha-Clopenthixol; Clopenthixol; Zuclopenthixol )

产品货号. M18758 CAS No. 53772-83-1

Zuclopenthixol is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.

纯度: 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
25MG ¥243 有现货
50MG ¥316 有现货
100MG ¥446 有现货
200MG ¥648 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Zuclopenthixol
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Zuclopenthixol is a thioxanthene with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors.
  • 产品描述
    Zuclopenthixol, also known as Cisordinol, Clopixol, Acuphase, zuclopentixol, is a typical antipsychotic drug of the thioxanthene class. It was introduced in 1962 by Lundbeck. Zuclopenthixol is the cis-isomer of clopenthixol. Zuclopenthixol is not approved for use in the United States. Zuclopenthixol has high affinity for both dopamine D1 and D2 receptors, for α1-adrenoceptors and 5-HT2 receptors but no affinity for cholinergic muscarine receptors. It has weak histamine (H1) receptor affinity and no α2-adrenoceptor blocking activity.
  • 同义词
    alpha-Clopenthixol; Clopenthixol; Zuclopenthixol
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    D1; D2
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    53772-83-1
  • 分子量
    400.96
  • 分子式
    C22H25ClN2OS
  • 纯度
    98%
  • 溶解度
    DMSO : ≥ 150 mg/mL; 374.10 mM
  • SMILES
    C1CN(CCN1CC/C=C\1/c2ccccc2Sc2c1cc(cc2)Cl)CCO
  • 化学全称
    2-[4-[(3Z)-3-(2-chlorothioxanthen-9-ylidene)propyl]piperazin-1-yl]ethanol

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Khalifa AE: Zuclopenthixol facilitates memory retrieval in rats: possible involvement of noradrenergic and serotonergic mechanisms. Pharmacol Biochem Behav. 2003 Jul;75(4):755-62.
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