
N-Boc-PEG5-bromide
CAS No. 1392499-32-9
N-Boc-PEG5-bromide ( —— )
产品货号. M26767 CAS No. 1392499-32-9
N-Boc-PEG5-bromide 是一种可裂解的 ADC 连接体,用于合成抗体药物偶联物 (ADC)。 N-Boc-PEG5-bromide 是一种基于 PEG 和烷基/醚的 PROTAC 连接体。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
100MG | ¥340 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称N-Boc-PEG5-bromide
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述N-Boc-PEG5-bromide 是一种可裂解的 ADC 连接体,用于合成抗体药物偶联物 (ADC)。 N-Boc-PEG5-bromide 是一种基于 PEG 和烷基/醚的 PROTAC 连接体。
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产品描述N-Boc-PEG5-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-PEG5-bromide is a PROTAC linker based on PEG and Alkyl/ether.(In Vitro):ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
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体外实验PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体ACSS2
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研究领域——
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适应症——
化学信息
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CAS Number1392499-32-9
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分子量400.31
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分子式C15H30BrNO6
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纯度>98% (HPLC)
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溶解度——
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SMILESCC(C)(C)OC(=O)NCCOCCOCCOCCOCCBr
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.?Dixon, Darryl David, et al. Benzimidazole derivatives as ACSS2 modulators and their preparation. WO2015175845A1
产品手册




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