N-Boc-PEG5-bromide ( —— )

产品货号. M26767 CAS No. 1392499-32-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

N-Boc-PEG5-bromide
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

N-Boc-PEG5-bromide 是一种可裂解的 ADC 连接体，用于合成抗体药物偶联物 (ADC)。 N-Boc-PEG5-bromide 是一种基于 PEG 和烷基/醚的 PROTAC 连接体。
产品描述

N-Boc-PEG5-bromide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Boc-PEG5-bromide is a PROTAC linker based on PEG and Alkyl/ether.(In Vitro):ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
体外实验

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
体内实验

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同义词

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通路

Others
靶点

Other Targets
受体

ACSS2
研究领域

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适应症

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1.?Dixon, Darryl David, et al. Benzimidazole derivatives as ACSS2 modulators and their preparation. WO2015175845A1

计算器

产品手册

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