Zotepine ( —— )

产品货号. M27130 CAS No. 26615-21-4

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HNMR

HPLC

MSDS

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产品名称

Zotepine
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT2A, 5-HT2C, Histamine H1, α1-adrenergic, and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM, 3.3 nM, 7.3 nM, and 8 nM, respectively.
产品描述

Zotepine, an antipsychotic agent, is a potent antagonist of 5-HT2A, 5-HT2C, Histamine H1, α1-adrenergic, and Dopamine D2 receptors, with Kds of 2.6 nM, 3.2 nM, 3.3 nM, 7.3 nM, and 8 nM, respectively. Zotepine is a second-generation antipsychotic with a primary use as a treatment for schizophrenia, although clinical trials have been conducted into its efficacy as an antimanic agent in patients with acute bipolar mania.
同义词

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通路

GPCR/G Protein
靶点

Dopamine Receptor
受体

Gpx4
研究领域

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适应症

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1.Kathman SG, et al. A masked zinger to block GPX4. Nat Chem Biol. 2020;16(5):482-483.

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