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XEN723

CAS No. 1072803-08-7

XEN723 ( —— )

产品货号. M23280 CAS No. 1072803-08-7

XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥1596 有现货
10MG ¥2535 有现货
25MG ¥4317 有现货
50MG ¥6221 有现货
100MG ¥8748 有现货
500MG ¥17496 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    XEN723
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor.
  • 产品描述
    XEN723 is a potent thiazolylimidazolidinone Stearoyl-CoA Desaturase (SCD1) inhibitor(IC50s of 45 and 524 nM in mouse and HepG2 cell, respectively).
  • 同义词
    ——
  • 通路
    Metabolic Enzyme/Protease
  • 靶点
    Dehydrogenase
  • 受体
    SCD1
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1072803-08-7
  • 分子量
    425.5
  • 分子式
    C21H20FN5O2S
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:100 mg/mL (235.03 mM; Need ultrasonic)
  • SMILES
    Cc1c(C(NCc2cnccc2)=O)sc(N(CCN2Cc(cc3)ccc3F)C2=O)n1
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Sun S, et al. Systematic evaluation of amide bioisosteres leading to the discovery of novel and potent thiazolylimidazolidinone inhibitors of SCD1 for the treatment of metabolic diseases. Bioorg Med Chem Lett. 2014 Jan 15;24(2):520-5.
产品手册
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