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Vorinostat
CAS No. 149647-78-9
Vorinostat ( SAHA;Suberoylanilide hydroxamic acid;MK-0683 )
产品货号. M12074 CAS No. 149647-78-9
A potent HDAC inhibitor, inhibits the activities of HDAC1 and HDAC3 with IC50 of 10 nM and 20 nM, respectively.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 200MG | ￥356 | 有现货 |
|
| 500MG | ￥697 | 有现货 |
|
| 1G | ￥818 | 有现货 |
|
生物学信息
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产品名称Vorinostat
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A potent HDAC inhibitor, inhibits the activities of HDAC1 and HDAC3 with IC50 of 10 nM and 20 nM, respectively.
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产品描述A potent HDAC inhibitor, inhibits the activities of HDAC1 and HDAC3 with IC50 of 10 nM and 20 nM, respectively; inhibits cell growth, induce terminal differentiation and prevent the formation of tumours in mice models.Blood Cancer Approved
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同义词SAHA;Suberoylanilide hydroxamic acid;MK-0683
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通路Cell Cycle/DNA Damage
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靶点HDAC
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受体HDAC;HDAC1;HDAC2;HDAC3;HDAC6;HDAC8
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研究领域Cancer
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适应症Blood cancer
化学信息
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CAS Number149647-78-9
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分子量264.32
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分子式C14H20N2O3
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纯度>98% (HPLC)
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溶解度DMSO: ≥ 100 mg/mL
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SMILESO=C(NO)CCCCCCC(NC1=CC=CC=C1)=O
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化学全称Octanediamide, N1-hydroxy-N8-phenyl-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Richon VM, et al. Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):3003-7.
2. Finnin MS, et al. Nature. 1999 Sep 9;401(6749):188-93.
3. Vrana JA, et al. Oncogene. 1999 Nov 25;18(50):7016-25.
4. Richon VM, et al. Proc Natl Acad Sci U S A. 2000 Aug 29;97(18):10014-9.
2. Finnin MS, et al. Nature. 1999 Sep 9;401(6749):188-93.
3. Vrana JA, et al. Oncogene. 1999 Nov 25;18(50):7016-25.
4. Richon VM, et al. Proc Natl Acad Sci U S A. 2000 Aug 29;97(18):10014-9.
产品手册
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