Vorinostat ( SAHA;Suberoylanilide hydroxamic acid;MK-0683 )

产品货号. M12074 CAS No. 149647-78-9

A potent HDAC inhibitor, inhibits the activities of HDAC1 and HDAC3 with IC50 of 10 nM and 20 nM, respectively.

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
200MG	￥356	有现货
500MG	￥697	有现货
1G	￥818	有现货

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生物学信息

产品名称

Vorinostat
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

A potent HDAC inhibitor, inhibits the activities of HDAC1 and HDAC3 with IC50 of 10 nM and 20 nM, respectively.
产品描述

A potent HDAC inhibitor, inhibits the activities of HDAC1 and HDAC3 with IC50 of 10 nM and 20 nM, respectively; inhibits cell growth, induce terminal differentiation and prevent the formation of tumours in mice models.Blood Cancer Approved
同义词

SAHA;Suberoylanilide hydroxamic acid;MK-0683
通路

Cell Cycle/DNA Damage
靶点

HDAC
受体

HDAC;HDAC1;HDAC2;HDAC3;HDAC6;HDAC8
研究领域

Cancer
适应症

Blood cancer

化学信息

CAS Number

149647-78-9
分子量

264.32
分子式

C14H20N2O3
纯度

>98% (HPLC)
溶解度

DMSO: ≥ 100 mg/mL
SMILES

O=C(NO)CCCCCCC(NC1=CC=CC=C1)=O
化学全称

Octanediamide, N1-hydroxy-N8-phenyl-

运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1. Richon VM, et al. Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):3003-7.
2. Finnin MS, et al. Nature. 1999 Sep 9;401(6749):188-93.
3. Vrana JA, et al. Oncogene. 1999 Nov 25;18(50):7016-25.
4. Richon VM, et al. Proc Natl Acad Sci U S A. 2000 Aug 29;97(18):10014-9.

计算器

浓度计算器

摩尔计算器

分子量计算器

产品手册

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