021-51111890
购物车（）
sales@molnova.cn
VTP50469
CAS No. 2169916-18-9
VTP50469 ( —— )
产品货号. M23981 CAS No. 2169916-18-9
VTP50469 is a highly selective and orally active inhibitor of Menin-MLL interaction( Ki: 104 pM) and has potently anti-leukemia activity.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥3029 | 有现货 |
|
| 10MG | ￥4836 | 有现货 |
|
| 25MG | ￥7808 | 有现货 |
|
| 50MG | ￥10449 | 有现货 |
|
| 100MG | ￥14256 | 有现货 |
|
| 200MG | ￥19197 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称VTP50469
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述VTP50469 is a highly selective and orally active inhibitor of Menin-MLL interaction( Ki: 104 pM) and has potently anti-leukemia activity.
-
产品描述VTP50469 is a highly selective and orally active inhibitor of Menin-MLL interaction( Ki: 104 pM) and has potently anti-leukemia activity.
-
同义词——
-
通路Apoptosis
-
靶点Apoptosis
-
受体Apoptosis;Menin-MLL interaction
-
研究领域——
-
适应症——
化学信息
-
CAS Number2169916-18-9
-
分子量630.8
-
分子式C32H47FN6O4S
-
纯度>98% (HPLC)
-
溶解度DMSO:125 mg/mL (198.15 mM; Need ultrasonic)
-
SMILESCC(C)N(C(C)C)C(=O)C1=C(C=CC(=C1)F)OC2=CN=CN=C2N3CC4(C3)CCN(CC4)CC5CCC(CC5)NS(=O)(=O)C
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Krivtsov AV, et al. A Menin-MLL Inhibitor Induces Specific Chromatin Changes and Eradicates Disease in Models of MLL-Rearranged Leukemia. Cancer Cell. 2019 Dec 9;36(6):660-673.e11.
产品手册
关联产品
-
RA-9
RA-9 is a potent and selective proteasome-associated inhibitor of deubiquitinating enzymes (DUBs), with favorable toxicity profile and anticancer activity.
-
Pitstop 2
Pitstop 2 is a inhibitor of clathrin, and inhibits clathrin-mediated endocytosis (CME) by associating with the terminal domain of clathrin. It has the potential for anti-cancer research.
-
Silvestrol
Silvestrol is a potential anticancer rocaglate derivative from Aglaia foveolata, induces apoptosis in cancer cells through the mitochondrial/apoptosome pathway.
