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USP8-IN-22c

CAS No. 924296-17-3

USP8-IN-22c ( —— )

产品货号. M16621 CAS No. 924296-17-3

A potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.56 uM.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥1604 有现货
5MG ¥2778 有现货
10MG ¥3969 有现货
25MG ¥6342 有现货
50MG ¥8829 有现货
100MG ¥11988 有现货
500MG ¥23895 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    USP8-IN-22c
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.56 uM.
  • 产品描述
    A potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.56 uM; shows no inhibitory activity for USP7, USP5, SENP1, Uch-L3, and caspase 3 (IC50>100 uM), and displays partial activity against Uch-L3; inhibits the viability of HCT116 colon and PC-3 prostate cancer cell lines with IC50 values in the 0.5-1.5 uM range.
  • 同义词
    ——
  • 通路
    Proteasome/Ubiquitin
  • 靶点
    DUB
  • 受体
    DUB
  • 研究领域
    Cancer
  • 适应症
    ——

化学信息

  • CAS Number
    924296-17-3
  • 分子量
    287.28
  • 分子式
    C16H9N5O
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: 20.1 mg/mL
  • SMILES
    C=CCON=C1C2=CC=CC=C2C3=NC(=C(N=C31)C#N)C#N
  • 化学全称
    9H-Indeno[1,2-b]pyrazine-2,3-dicarbonitrile, 9-[(2-propen-1-yloxy)imino]-

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Colombo M, et al. ChemMedChem. 2010 Apr 6;5(4):552-8.
产品手册
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