021-51111890
购物车（）
sales@molnova.cn
USP8-IN-22c
CAS No. 924296-17-3
USP8-IN-22c ( —— )
产品货号. M16621 CAS No. 924296-17-3
A potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.56 uM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥1604 | 有现货 |
|
| 5MG | ￥2778 | 有现货 |
|
| 10MG | ￥3969 | 有现货 |
|
| 25MG | ￥6342 | 有现货 |
|
| 50MG | ￥8829 | 有现货 |
|
| 100MG | ￥11988 | 有现货 |
|
| 500MG | ￥23895 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称USP8-IN-22c
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述A potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.56 uM.
-
产品描述A potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.56 uM; shows no inhibitory activity for USP7, USP5, SENP1, Uch-L3, and caspase 3 (IC50>100 uM), and displays partial activity against Uch-L3; inhibits the viability of HCT116 colon and PC-3 prostate cancer cell lines with IC50 values in the 0.5-1.5 uM range.
-
同义词——
-
通路Proteasome/Ubiquitin
-
靶点DUB
-
受体DUB
-
研究领域Cancer
-
适应症——
化学信息
-
CAS Number924296-17-3
-
分子量287.28
-
分子式C16H9N5O
-
纯度>98% (HPLC)
-
溶解度DMSO: 20.1 mg/mL
-
SMILESC=CCON=C1C2=CC=CC=C2C3=NC(=C(N=C31)C#N)C#N
-
化学全称9H-Indeno[1,2-b]pyrazine-2,3-dicarbonitrile, 9-[(2-propen-1-yloxy)imino]-
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Colombo M, et al. ChemMedChem. 2010 Apr 6;5(4):552-8.
产品手册
关联产品
-
USP7-IN-8
USP7-IN-8 is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 μM. USP7-IN-8 has anticancer effects.
-
USP8-IN-22d
A potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.85 uM.
-
GNE-6640
GNE-6640 (GNE6640) is a potent, selective USP7 inhibitor with IC50 of 0.75 uM.
