USP8-IN-22c
CAS No. 924296-17-3
USP8-IN-22c ( —— )
产品货号. M16621 CAS No. 924296-17-3
A potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.56 uM.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥1604 | 有现货 |
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5MG | ¥2778 | 有现货 |
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10MG | ¥3969 | 有现货 |
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25MG | ¥6342 | 有现货 |
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50MG | ¥8829 | 有现货 |
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100MG | ¥11988 | 有现货 |
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500MG | ¥23895 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称USP8-IN-22c
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述A potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.56 uM.
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产品描述A potent, selective ubiquitin-specific protease USP8 inhibitor with IC50 of 0.56 uM; shows no inhibitory activity for USP7, USP5, SENP1, Uch-L3, and caspase 3 (IC50>100 uM), and displays partial activity against Uch-L3; inhibits the viability of HCT116 colon and PC-3 prostate cancer cell lines with IC50 values in the 0.5-1.5 uM range.
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同义词——
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通路Proteasome/Ubiquitin
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靶点DUB
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受体DUB
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研究领域Cancer
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适应症——
化学信息
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CAS Number924296-17-3
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分子量287.28
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分子式C16H9N5O
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纯度>98% (HPLC)
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溶解度DMSO: 20.1 mg/mL
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SMILESC=CCON=C1C2=CC=CC=C2C3=NC(=C(N=C31)C#N)C#N
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化学全称9H-Indeno[1,2-b]pyrazine-2,3-dicarbonitrile, 9-[(2-propen-1-yloxy)imino]-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Colombo M, et al. ChemMedChem. 2010 Apr 6;5(4):552-8.