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UAMC3203
CAS No. 2271358-64-4
UAMC3203 ( UAMC 3203 | UAMC-3203 )
产品货号. M20094 CAS No. 2271358-64-4
UAMC-3203 是一种有效的选择性铁死亡抑制剂 (IC50: 12 nM)。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥567 | 有现货 |
|
| 10MG | ￥907 | 有现货 |
|
| 25MG | ￥1523 | 有现货 |
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| 50MG | ￥2292 | 有现货 |
|
| 100MG | ￥3418 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称UAMC3203
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述UAMC-3203 是一种有效的选择性铁死亡抑制剂 (IC50: 12 nM)。
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产品描述UAMC-3203 is a potent and selective Ferroptosis inhibitor (IC50: 12 nM).
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体外实验——
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体内实验No toxicity is observed in mice after repeated injections of UAMC-3203 (20 μmol/kg; injected intraperitoneally; daily, over a period of 4 weeks). Animal Model:Wild type mice derived from a Gpx4 fl/fl breeding Dosage:20 μmol/kg Administration:Injected intraperitoneally; daily, over a period of 4 weeks Result:No toxicity was observed.
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同义词UAMC 3203 | UAMC-3203
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通路Apoptosis
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靶点Ferroptosis
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受体Ferroptosis
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研究领域——
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适应症——
化学信息
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CAS Number2271358-64-4
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分子量471.66
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分子式C25H37N5O2S
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纯度>98% (HPLC)
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溶解度DMSO:199.3 mM
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SMILESO=S(=O)(NCCN1CCNCC1)c1ccc(NC2CCCCC2)c(NCc2ccccc2)c1
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Devisscher L et al. Discovery of Novel Drug-Like Ferroptosis Inhibitors with in Vivo Efficacy. J Med Chem. 2018 Nov 21;61(22):10126-10140.
