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Tucidinostat
CAS No. 1616493-44-7
Tucidinostat ( Chidamide;HBI-8000;CS055 )
产品货号. M12363 CAS No. 1616493-44-7
Tucidinostat (Chidamide, HBI-8000, CS055) is a novel histone deacetylase (HDAC) inhibitor.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥470 | 有现货 |
|
| 10MG | ￥745 | 有现货 |
|
| 25MG | ￥1385 | 有现货 |
|
| 50MG | ￥2244 | 有现货 |
|
| 100MG | ￥3588 | 有现货 |
|
| 200MG | ￥5030 | 有现货 |
|
| 500MG | ￥7493 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Tucidinostat
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Tucidinostat (Chidamide, HBI-8000, CS055) is a novel histone deacetylase (HDAC) inhibitor.
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产品描述Tucidinostat (Chidamide, HBI-8000, CS055) is a novel histone deacetylase (HDAC) inhibitor with IC50 of 95/160/67/733/78/432 nM for HDAC1/2/3/8/10/11, respectively; shows no activity against Class IIa HDAC4/4/7/9 and HDAC6; demonstrates significant and broad spectrum in vitro and in vivo antitumor activity, induces G1 arrest, ROS-dependent apoptosis and differentiation in human leukaemia cells.Blood Cancer Approved
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同义词Chidamide;HBI-8000;CS055
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通路Cell Cycle/DNA Damage
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靶点HDAC
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受体HDAC1;HDAC2;HDAC3;HDAC10
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研究领域Cancer
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适应症Blood cancer
化学信息
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CAS Number1616493-44-7
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分子量390.42
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分子式C22H19FN4O2
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纯度>98% (HPLC)
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溶解度Ethanol: 1 mg/mL Water: InsolubleDMSO: 50 mg/mL （ < 1 mg/ml refers to the product slightly soluble or insoluble )
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SMILESO=C(NC1=CC=C(F)C=C1N)C2=CC=C(CNC(/C=C/C3=CC=CN=C3)=O)C=C2
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化学全称N-(2-amino-4-fluorophenyl)-4-[[[(E)-3-pyridin-3-ylprop-2-enoyl]amino]methyl]benzamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Ning ZQ, et al. Cancer Chemother Pharmacol. 2012 Apr;69(4):901-9.
2. Gong K, et al. Biochem J. 2012 May 1;443(3):735-46.
3. Dong M, et al. Cancer Chemother Pharmacol. 2012 Jun;69(6):1413-22.
4. Gao S, et al. Anticancer Agents Med Chem. 2017;17(6):802-812.
2. Gong K, et al. Biochem J. 2012 May 1;443(3):735-46.
3. Dong M, et al. Cancer Chemother Pharmacol. 2012 Jun;69(6):1413-22.
4. Gao S, et al. Anticancer Agents Med Chem. 2017;17(6):802-812.
产品手册
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