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Thalidomide-5-methyl
CAS No. 40313-92-6
Thalidomide-5-methyl ( —— )
产品货号. M28307 CAS No. 40313-92-6
Thalidomide-5-methyl 是基于沙利度胺的 cereblon (CRBN) 配体，用于招募 CRBN 蛋白。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥3540 | 有现货 |
|
| 10MG | ￥5233 | 有现货 |
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| 25MG | ￥7995 | 有现货 |
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| 50MG | ￥11178 | 有现货 |
|
| 100MG | ￥15066 | 有现货 |
|
| 500MG | ￥30132 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Thalidomide-5-methyl
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Thalidomide-5-methyl 是基于沙利度胺的 cereblon (CRBN) 配体，用于招募 CRBN 蛋白。
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产品描述Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.(In Vitro):PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins .
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体外实验PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体hDHODH
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研究领域——
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适应症——
化学信息
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CAS Number40313-92-6
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分子量272.26
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分子式C14H12N2O4
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纯度>98% (HPLC)
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溶解度——
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SMILESCc(cc1)cc(C(N2C(CCC(N3)=O)C3=O)=O)c1C2=O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Lewis TA, et al. Development?of?ML390: A?Human?DHODH?Inhibitor?That?Induces?Differentiation?in?Acute?Myeloid?Leukemia. ACS Med Chem Lett.?2016 Sep 28;7(12):1112-1117.
