021-51111890
购物车（）
sales@molnova.cn
HC-067047
CAS No. 883031-03-6
HC-067047 ( HC-067047; HC 067047; HC067047 )
产品货号. M19226 CAS No. 883031-03-6
HC-067047 is a potent and selective TRPV4 antagonist.Also inhibits the endogenous TRPV4-mediated response to 4α-PDH .
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥502 | 有现货 |
|
| 10MG | ￥794 | 有现货 |
|
| 25MG | ￥1604 | 有现货 |
|
| 50MG | ￥2657 | 有现货 |
|
| 100MG | ￥4277 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称HC-067047
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述HC-067047 is a potent and selective TRPV4 antagonist.Also inhibits the endogenous TRPV4-mediated response to 4α-PDH .
-
产品描述HC-067047 is a potent and selective TRPV4 antagonist. HC-067047 increases functional bladder capacity and reduces micturition frequency in WT mice and rats with cystitis. HC-067047 did not affect bladder function in Trpv4(-/-) mice, demonstrating that its in vivo effects are on target. HC-067047 may provide a promising means of treating bladder
-
同义词HC-067047; HC 067047; HC067047
-
通路Others
-
靶点Other Targets
-
受体hTRPV4/mTRPV4
-
研究领域Cancer
-
适应症——
化学信息
-
CAS Number883031-03-6
-
分子量471.51
-
分子式C26H28F3N3O2
-
纯度98%
-
溶解度DMSO : 50 mg/mL 106.04 mM;
-
SMILESFC(F)(F)c1cc(ccc1)NC(=O)c4cc(c2ccccc2)n(CCCN3CCOCC3)c4C
-
化学全称2-Methyl-1-[3-(4-morpholinyl)propyl]-5-phenyl-N-[3-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1.Everaerts W et al. Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis.Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):19084-9.
产品手册
关联产品
-
Nitroxazepine
Nitroxazepine is a serotonin-norepinephrine reuptake inhibitor, and treatment depression. Nitroxazepine is a tricyclic antidepressant (TCA) for the research of depression
-
Methyl nomilinate
Methyl nomilinate from citrus can modulate cell cycle regulators to induce cytotoxicity in human colon cancer (SW480) cells in vitro.
-
Cussosaponin C
Cussosaponin C is a natural product isolated from Pulsatilla koreana Nakai.
