• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

Teriflunomide

CAS No. 108605-62-5

Teriflunomide ( A77 1726; HMR 1726; teriflunomide; Brande name: Aubagio. )

产品货号. M10335 CAS No. 108605-62-5

Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis.

纯度: >98%(HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
25MG ¥405 有现货
50MG ¥462 有现货
100MG ¥599 有现货
200MG ¥786 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Teriflunomide
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis.
  • 产品描述
    Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. It is marketed under the name Aubagio and is indicated for the treatment of multiple sclerosis, specifically relapsing forms.
  • 同义词
    A77 1726; HMR 1726; teriflunomide; Brande name: Aubagio.
  • 通路
    Metabolic Enzyme/Protease
  • 靶点
    Dehydrogenase
  • 受体
    Dihydroorotate Dehydrogenase
  • 研究领域
    Inflammation/Immunology
  • 适应症
    ——

化学信息

  • CAS Number
    108605-62-5
  • 分子量
    270.21
  • 分子式
    C12H9F3N2O2
  • 纯度
    >98%(HPLC)
  • 溶解度
    Ethanol: 1 mg/mL ,1; Water: <1 mg/mL (<1 mM); DMSO: 32 mg/mL (118.42 mM)
  • SMILES
    C/C(O)=C(C#N)/C(NC1=CC=C(C(F)(F)F)C=C1)=O
  • 化学全称
    (Z)-2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)but-2-enamide.

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Palmer AM. Curr Opin Investig Drugs. 2010 Nov;11(11):1313-23.
产品手册
关联产品
  • hDHODH-IN-5

    hDHODH-IN-5 is an inhibitor of human dihydroorotate dehydrogenase.

  • Nitrophenide

    Nitrophenide inhibits mannitol-1-phosphate dehydrogenase (M1PDH), which catalyzes the committed enzymatic step in the mannitol cycle. Nitrophenide can be used as an anticoccidial agent.

  • WAY-324168

    WAY-324168 is a compound with antiproliferative activity.