Telratolimod

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Telratolimod 是一种 Toll 样受体 7/8 激动剂。它具有抗肿瘤活性。

Telratolimod is a toll-like receptors 7/8 agonist. It has an antitumor activity.(In Vivo):Telratolimod (50 μg) suppresses the tumor volume and more effectively blocks tumor growth in combination with CpG ODN in BALB/c mice bearing CT26 colon carcinoma cells. Telratolimod (100 μg) plus 200 μg of CpG ODN slows tumor growth and prolongs the survival of mice bearing large tumors .

Telratolimod (3M-052) is a toll like receptors 7/8 (TLR7/8) agonist, with antitumor activity.

Telratolimod (50 μg) inhibits the tumor volume, and more potently blocks tumor gowth in combination with CpG ODN in BALB/c mice bearing CT26 colon carcinoma cells. Telratolimod (100 μg) plus 200 μg of CpG ODN slows tumor growth and prolongs survival of mice bearing large tumors.

MEDI9197 | 3M-052

Immunology/Inflammation

TLR

LpxC

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——

1359993-59-1

593.901

C36H59N5O2

>98% (HPLC)

In Vitro:?DMSO : 62.5 mg/mL (105.24 mM)

CCCCCCCCCCCCCCCCCC(=O)NCCCCOn1c(CCCC)nc2c(N)nc3ccccc3c12

——

(-20℃)

With Ice Pack

≥ 2 years