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Telatinib
CAS No. 332012-40-5
Telatinib ( Bay 57-9352 )
产品货号. M14115 CAS No. 332012-40-5
An orally active, small molecule inhibitor of VEGFR-2 (IC50=6 nM), VEGFR-3 (IC50=4 nM), PDEGFRα (IC50=15 nM) and c-Kit (IC50=1 nM) in biochemical assays.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥316 | 有现货 |
|
| 10MG | ￥446 | 有现货 |
|
| 25MG | ￥988 | 有现货 |
|
| 50MG | ￥1596 | 有现货 |
|
| 100MG | ￥2981 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Telatinib
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述An orally active, small molecule inhibitor of VEGFR-2 (IC50=6 nM), VEGFR-3 (IC50=4 nM), PDEGFRα (IC50=15 nM) and c-Kit (IC50=1 nM) in biochemical assays.
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产品描述An orally active, small molecule inhibitor of VEGFR-2 (IC50=6 nM), VEGFR-3 (IC50=4 nM), PDEGFRα (IC50=15 nM) and c-Kit (IC50=1 nM) in biochemical assays.Gastric Cancer Phase 2 Clinical
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同义词Bay 57-9352
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通路Angiogenesis
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靶点VEGFR
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受体c-Kit;PDGFRα;VEGFR2;VEGFR3
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研究领域Cancer
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适应症Gastric Cancer
化学信息
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CAS Number332012-40-5
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分子量409.83
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分子式C20H16ClN5O3
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纯度>98% (HPLC)
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溶解度DMSO: ≥ 46 mg/mL
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SMILESO=C(C1=NC=CC(COC2=NN=C(NC3=CC=C(Cl)C=C3)C4=C2OC=C4)=C1)NC
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化学全称2-Pyridinecarboxamide, 4-[[[4-[(4-chlorophenyl)amino]furo[2,3-d]pyridazin-7-yl]oxy]methyl]-N-methyl-
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Steeghs N, et al. Clin Cancer Res. 2008 Jun 1;14(11):3470-6.
2. Strumberg D, et al. Br J Cancer. 2008 Nov 18;99(10):1579-85.
3. Sodani K, et al. Biochem Pharmacol. 2014 May 1;89(1):52-61.
2. Strumberg D, et al. Br J Cancer. 2008 Nov 18;99(10):1579-85.
3. Sodani K, et al. Biochem Pharmacol. 2014 May 1;89(1):52-61.
产品手册
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