021-51111890
购物车（）
sales@molnova.cn
TMP-153
CAS No. 128831-46-9
TMP-153 ( TMP153 )
产品货号. M11175 CAS No. 128831-46-9
TMP-153 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor with IC50 of 5-10 nM for the hepatic and intestinal ACAT from various animals.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥7857 | 有现货 |
|
| 50MG | ￥16038 | 有现货 |
|
| 100MG | ￥20250 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称TMP-153
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述TMP-153 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor with IC50 of 5-10 nM for the hepatic and intestinal ACAT from various animals.
-
产品描述TMP-153 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor with IC50 of 5-10 nM for the hepatic and intestinal ACAT from various animals; inhibits cholesterol esterification both in human colonic adenocarcinoma cells, LS180, and in human hepatoma cells, HepG2 (IC50 = 150 nM and 330 nM, respectively); inhibits cholesterol absorption and lowers plasma cholesterol in rats and hamsters.Hypercholesterolemia Discontinued
-
同义词TMP153
-
通路Others
-
靶点Other Targets
-
受体Other Targets
-
研究领域Cardiovascular Disease
-
适应症Hypercholesterolemia
化学信息
-
CAS Number128831-46-9
-
分子量437.90
-
分子式C24H18ClF2N3O
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESCC1=CC2=C(C(=CN=C2C=C1C)NC(=O)NC3=C(C=C(C=C3)F)F)C4=CC=CC=C4Cl
-
化学全称N-[4-(2-chlorophenyl)-6,7-dimethyl-3-quinolinyl]-N'-(2,4-difluorophenyl)-urea
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Sugiyama Y, et al. Atherosclerosis. 1995 Feb;113(1):71-8.
2. Sugiyama Y, et al. Atherosclerosis. 1995 Nov;118(1):145-53.
3. Tawada H, et al. J Med Chem. 1994 Jun 24;37(13):2079-84.
2. Sugiyama Y, et al. Atherosclerosis. 1995 Nov;118(1):145-53.
3. Tawada H, et al. J Med Chem. 1994 Jun 24;37(13):2079-84.
