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首页- Products - GPCR/G Protein - Antibacterial - Solithromycin

Solithromycin

CAS No. 760981-83-7

Solithromycin ( CEM-101;OP-1068 )

产品货号. M15888 CAS No. 760981-83-7

A novel fluoroketolide with lower MICs than those of telithromycin and macrolides.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ￥259 有现货
5MG ￥413 有现货
10MG ￥721 有现货
25MG ￥1442 有现货
50MG ￥2373 有现货
100MG 获取报价 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货
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生物学信息

  • 产品名称
    Solithromycin
  • 注意事项
    本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
  • 产品简述
    A novel fluoroketolide with lower MICs than those of telithromycin and macrolides.
  • 产品描述
    A novel fluoroketolide with lower MICs than those of telithromycin and macrolides; binds to the large 50S subunit of the ribosome and inhibits protein biosynthesis; exhibits MICs of 7.5, 40, and 125 ng/ml for Streptococcus pneumoniae,Staphylococcus aureus, and Haemophilus influenzae, respectively. Bacterial Infection Approved
  • 同义词
    CEM-101;OP-1068
  • 通路
    GPCR/G Protein
  • 靶点
    Antibacterial
  • 受体
    Antibiotic
  • 研究领域
    Infection
  • 适应症
    Bacterial Infection

化学信息

  • CAS Number
    760981-83-7
  • 分子量
    845.01
  • 分子式
    C43H65FN6O10
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO: ≥ 32 mg/mL
  • SMILES
    CC[C@@H]1[C@@]2([C@@H]([C@@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H](C(=O)[C@@](C(=O)O1)(C)F)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)OC)C)C)N(C(=O)O2)CCCCN4C=C(N=N4)C5=CC(=CC=C5)N)C
  • 化学全称
    2H-Oxacyclotetradecino[4,3-d]oxazole-2,6,8,14(1H,7H,9H)-tetrone, 1-[4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl]-4-ethyl-7-fluorooctahydro-11-methoxy-3a,7,9,11,13,15-hexamethyl-10-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-, (3aS,

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Waites KB, et al. Antimicrob Agents Chemother. 2009 May;53(5):2139-41.
2. Lemaire S, et al. Antimicrob Agents Chemother. 2009 Sep;53(9):3734-43.
3. Roblin PM, et al. Antimicrob Agents Chemother. 2010 Mar;54(3):1358-9.
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