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CRS-3123

CAS No. 1013915-71-3

CRS-3123 ( CRS3123;REP 3123 )

产品货号. M10078 CAS No. 1013915-71-3

A novel diaryldiamine that inhibits bacterial methionyl-tRNA synthetases in Gram-positive bacteria as a novel agent to treat Clostridium difficile infection (CDI).

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥11907 有现货
50MG ¥24138 有现货
100MG ¥32400 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    CRS-3123
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    A novel diaryldiamine that inhibits bacterial methionyl-tRNA synthetases in Gram-positive bacteria as a novel agent to treat Clostridium difficile infection (CDI).
  • 产品描述
    A novel diaryldiamine that inhibits bacterial methionyl-tRNA synthetases in Gram-positive bacteria as a novel agent to treat Clostridium difficile infection (CDI); inhibits de novo toxin production in high cell density, stationary phase cultures of C. difficile at 1 mg/L; demonstrates efficacy in the hamster model of CDI and is superior to vancomycin 0.5 mg/kg in CDI model.Bacterial Infection Phase 1 Clinical
  • 同义词
    CRS3123;REP 3123
  • 通路
    GPCR/G Protein
  • 靶点
    Antibacterial
  • 受体
    Antibacterial
  • 研究领域
    Infection
  • 适应症
    Bacterial Infection

化学信息

  • CAS Number
    1013915-71-3
  • 分子量
    515.26
  • 分子式
    C19H21Br2N3O2S
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    BrC1=CC(Br)=C2OCC[C@H](C2=C1)NCCCNC3=CC(C4SC=CC4N3)=O
  • 化学全称
    5-((3-(((R)-6,8-dibromochroman-4-yl)amino)propyl)amino)-3a,7a-dihydrothieno[3,2-b]pyridin-7(4H)-one

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Citron DM, et al. J Antimicrob Chemother. 2009 May;63(5):972-6.
2. Ochsner UA, et al. J Antimicrob Chemother. 2009 May;63(5):964-71.
3. Critchley IA, et al. J Antimicrob Chemother. 2009 May;63(5):954-63.
产品手册
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