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CRS-3123
CAS No. 1013915-71-3
CRS-3123 ( CRS3123;REP 3123 )
产品货号. M10078 CAS No. 1013915-71-3
A novel diaryldiamine that inhibits bacterial methionyl-tRNA synthetases in Gram-positive bacteria as a novel agent to treat Clostridium difficile infection (CDI).
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥11907 | 有现货 |
|
| 50MG | ￥24138 | 有现货 |
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| 100MG | ￥32400 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称CRS-3123
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述A novel diaryldiamine that inhibits bacterial methionyl-tRNA synthetases in Gram-positive bacteria as a novel agent to treat Clostridium difficile infection (CDI).
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产品描述A novel diaryldiamine that inhibits bacterial methionyl-tRNA synthetases in Gram-positive bacteria as a novel agent to treat Clostridium difficile infection (CDI); inhibits de novo toxin production in high cell density, stationary phase cultures of C. difficile at 1 mg/L; demonstrates efficacy in the hamster model of CDI and is superior to vancomycin 0.5 mg/kg in CDI model.Bacterial Infection Phase 1 Clinical
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同义词CRS3123;REP 3123
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通路GPCR/G Protein
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靶点Antibacterial
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受体Antibacterial
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研究领域Infection
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适应症Bacterial Infection
化学信息
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CAS Number1013915-71-3
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分子量515.26
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分子式C19H21Br2N3O2S
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纯度>98% (HPLC)
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溶解度——
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SMILESBrC1=CC(Br)=C2OCC[C@H](C2=C1)NCCCNC3=CC(C4SC=CC4N3)=O
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化学全称5-((3-(((R)-6,8-dibromochroman-4-yl)amino)propyl)amino)-3a,7a-dihydrothieno[3,2-b]pyridin-7(4H)-one
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Citron DM, et al. J Antimicrob Chemother. 2009 May;63(5):972-6.
2. Ochsner UA, et al. J Antimicrob Chemother. 2009 May;63(5):964-71.
3. Critchley IA, et al. J Antimicrob Chemother. 2009 May;63(5):954-63.
2. Ochsner UA, et al. J Antimicrob Chemother. 2009 May;63(5):964-71.
3. Critchley IA, et al. J Antimicrob Chemother. 2009 May;63(5):954-63.
产品手册
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