Sirtinol ( Sirtinol )

产品货号. M18528 CAS No. 410536-97-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

Sirtinol
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Sirtinol is a selective SIRT1/2 inhibitor (IC50: 131/38 μM).
产品描述

Sirtinol is a SIRT inhibitor. Sirtinol significantly increased the acetylation of p53, which has been reported to be a target of SIRT1/2. Sirtinol significantly increased the G1 phase of the cell cycle.
同义词

Sirtinol
通路

Others
靶点

Other Targets
受体

SIRT1; SIRT2
研究领域

Cancer
适应症

——

CAS Number

410536-97-9
分子量

394.47
分子式

C26H22N2O2
纯度

98%
溶解度

DMSO : 6.5 mg/mL 16.48 mM;
SMILES

CC(c1ccccc1)NC(=O)c1ccccc1/N=C/c1c(O)ccc2ccccc12
化学全称

2-[[(2-Hydroxy-1-naphthalenyl)methylene]amino]- N -(1-phenylethyl)benzamide

1. Grozinger CM, et al. J Biol Chem, 2001, 276(42), 38837-38843.

计算器

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