
Ondansetron
CAS No. 99614-02-5
Ondansetron ( GRC50775 | SN307 )
产品货号. M19306 CAS No. 99614-02-5
Ondansetron 是一种 5-羟色胺 5-HT3 受体拮抗剂,主要用作止吐剂。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
25MG | ¥373 | 有现货 |
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100MG | ¥551 | 有现货 |
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200MG | ¥810 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Ondansetron
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Ondansetron 是一种 5-羟色胺 5-HT3 受体拮抗剂,主要用作止吐剂。
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产品描述This medication is used alone or with other medications to prevent nausea and vomiting caused by cancer drug treatment (chemotherapy) and radiation therapy. It is also used to prevent and treat nausea and vomiting after surgery. It works by blocking one of the body's natural substances (serotonin) that causes vomiting.
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体外实验——
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体内实验Animal Model:NSCLC Patients Treated With Chemotherapy Dosage:8 mg Administration:Intraperitoneal Injection (i.p.)Result:Showed TD50 and LD50 doses with 3.7±0.6 mg/kg and 4.6±0.5 mg/kg, respectively.Animal Model:Male Swiss Mice with Colitis Dosage:2 mg/kg Administration:Intraperitoneal Injection (i.p.)Result:Showed dramatic reduction in MPO activity and tumor necrosis factor-alpha, interleukin-6 and interleukin-1 beta.
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同义词GRC50775 | SN307
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通路Others
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靶点Other Targets
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受体5-HT3 receptor
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研究领域Cancer|Neurological Disease
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适应症——
化学信息
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CAS Number99614-02-5
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分子量293.36
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分子式C18H19N3O
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纯度>98% (HPLC)
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溶解度H2O : < 0.1 mg/mL DMSO : < 1 mg/mL
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SMILESCC1=NC=CN1CC2CCC3=C(C2=O)C4=CC=CC=C4N3C
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化学全称1, 2, 3, 9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1- yl)methyl]-4H-carbazol-4-one, monohydrochloride, dihydrate
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Haj-Mirzaian A, et al. Eur J Pharmacol. 2016 Mar 19. pii: S0014-2999(16)30157-1.
产品手册




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