
Toosendanin
CAS No. 58812-37-6
Toosendanin ( —— )
产品货号. M18857 CAS No. 58812-37-6
川楝素对人早幼粒细胞白血病 HL-6 细胞的生长、细胞周期阻滞、诱导细胞凋亡以及相关信号通路有影响。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
10MG | ¥882 | 有现货 |
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25MG | ¥1746 | 有现货 |
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100MG | 获取报价 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Toosendanin
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述川楝素对人早幼粒细胞白血病 HL-6 细胞的生长、细胞周期阻滞、诱导细胞凋亡以及相关信号通路有影响。
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产品描述Toosendanin possesses hepatotoxicity. Toosendanin has effects on the growth, cell cycle arrest, induction of apoptosis and the involved signaling pathway in human promyelocytic leukemia HL-6 cells. Toosendanin is an effective insecticide for Ae.
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体外实验——
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体内实验Toosendanin (0.5 and 1 mg/kg, Intraperitoneal injection daily for 7 days) alleviates DSS-induced experimental colitis by inhibiting M1 macrophage polarization and regulating NLRP3 inflammasome and Nrf2/HO-1 signaling, and may provide a novel Chinese patent medicine for the treatment of murine colitis. Animal Model:Forty-eight male C57BL/6 mice weighing 20-22 g.Dosage:0.5 and 1 mg/kg.Administration:Intraperitoneal injection daily for 7 days.Result:Protected against DSS-induced colitis in mice.Inhibited the expression of proinflammatory cytokines in DSS-induced UC and improved oxidative stress.
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同义词——
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通路Others
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靶点Other Targets
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受体Others
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研究领域Others-Field
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适应症——
化学信息
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CAS Number58812-37-6
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分子量574.62
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分子式C30H38O11
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 100 mg/mL (174.03 mM)
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SMILESCC(=O)OC1CC(C23COC(C1(C2CC(C4(C3C(=O)C(C5(C46C(O6)CC5C7=COC=C7)C)OC(=O)C)C)O)C)O)O
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
产品手册




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