Sesamolin

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

芝麻素通过抑制 p38 MAPK 和 caspase-3 激活以及 ROS 产生，保护小胶质细胞免受 H2O2 诱导的细胞损伤。

Sesamolin and Sesamin has neuroprotective effect. Sesamolin protects microglia against H2O2-induced cell injury, by inhibiting of p38 MAPK and caspase-3 activation and ROS production. Sesamolin and Sesamin can significantly attenuate the excess generation of nitric oxide in lipopolysaccharide-stimulated rat primary microglia cells.

——

——

Sesamolin | AI3-20978 | AI320978

Others

Other Targets

p38 MAPK|Caspase-3

——

——

526-07-8

370.35

C20H18O7

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (270.01 mM)

C1C2C(COC2OC3=CC4=C(C=C3)OCO4)C(O1)C5=CC6=C(C=C5)OCO6

1,3-Benzodioxole, 5-(4-(1,3-benzodioxol-5-yloxy)tetrahydro-1H,3H-furo(3,4-c)furan-1-yl)-, (1S-(1alpha,3a alpha,4alpha,6a alpha))-

(-20℃)

With Ice Pack

≥ 2 years