SJ830599 ( SJ 830599 )

产品货号. M13530 CAS No. 2215098-23-8

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

SJ830599
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

SJ830599 is a modest selective BRD2-BD2 inhibitor with IC50 of 0.61 uM, 3.3-fold selectivity over BRD2-BD1.
产品描述

SJ830599 is a modest selective BRD2-BD2 inhibitor with IC50 of 0.61 uM, 3.3-fold selectivity over BRD2-BD1; demonstrates cytotoxicity against several pediatric cancer cell lines with EC50 values (HD-MB03 EC50=480 nM) comparable to BET inhibitor (BETi) clinical candidates.
同义词

SJ 830599
通路

Chromatin/Epigenetic
靶点

Bromodomain
受体

Bromodomain
研究领域

——
适应症

——

CAS Number

2215098-23-8
分子量

356.42
分子式

C20H24N2O4
纯度

>98% (HPLC)
溶解度

——
SMILES

——
化学全称

Isopropyl ((2S,4R)-1-acetyl-6-(furan-2-yl)-2-methyl-1,2,3,4-tetrahydroquinolin-4-yl)carbamate

1. Shadrick WR, et al. Bioorg Med Chem. 2018 Jan 1;26(1):25-36.

计算器

产品手册

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