SCR-1481B1
CAS No. 1174161-86-4
SCR-1481B1 ( c-Met inhibitor 2 )
产品货号. M20163 CAS No. 1174161-86-4
SCR-1481B1 has activity against cancers dependent on Met activation and also has activity against cancers as a VEGFR inhibitor.
纯度: >98% (HPLC)
规格 | 价格/人民币 | 库存 | 数量 |
2MG | ¥365 | 有现货 |
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5MG | ¥583 | 有现货 |
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10MG | ¥988 | 有现货 |
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25MG | ¥1798 | 有现货 |
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50MG | ¥2989 | 有现货 |
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100MG | ¥4447 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称SCR-1481B1
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述SCR-1481B1 has activity against cancers dependent on Met activation and also has activity against cancers as a VEGFR inhibitor.
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产品描述SCR-1481B1 has activity against cancers dependent on Met activation and also has activity against cancers as a VEGFR inhibitor.
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同义词c-Met inhibitor 2
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通路Angiogenesis
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靶点VEGFR
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受体VEGFR1
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研究领域——
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适应症——
化学信息
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CAS Number1174161-86-4
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分子量742.07
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分子式C31H35ClF2N5O10P?
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纯度>98% (HPLC)
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溶解度DMSO:31 mg/mL?(44.29 mM)
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SMILESNC(CO)(CO)CO.NC(CO)(CO)CO.Nc1nccc(Oc2ccc(NC(=O)c3cn(COP(O)(O)=O)cc(-c4ccc(F)cc4)c3=O)cc2F)c1Cl
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
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Takeda-6d
Takeda-6d is a novel, potent DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitor with IC50 of 7.0 nM and 2.2 nM, respectively.
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Cabozantinib
Cabozantinib (XL184, BMS-907351) is a potent multi-kinase inhibitor that inhibits VEGFR2, c-Met, Kit, Axl and Flt3 with IC50 of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively.
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Lariciresinol
Lariciresinol is an enterolignan precursor, it possesses fungicidal activities by disrupting the fungal plasma membrane and therapeutic potential as a novel antifungal agent for the treatment of fungal infectious diseases in humans. Dietary lariciresinol can attenuate mammary tumor growth and reduce blood vessel density in human MCF-7 breast cancer xenografts and carcinogen-induced mammary tumors in rats.