021-51111890
购物车（）
sales@molnova.cn
SB-357134
CAS No. 219963-52-7
SB-357134 ( SB 357134;SB357134 )
产品货号. M13506 CAS No. 219963-52-7
A potent, selective, orally active and CNS penetrant 5-HT6 receptor antagonist with pKi of 8.5.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 5MG | ￥7857 | 有现货 |
|
| 50MG | ￥16038 | 有现货 |
|
| 100MG | ￥20250 | 有现货 |
|
| 200MG | 获取报价 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称SB-357134
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述A potent, selective, orally active and CNS penetrant 5-HT6 receptor antagonist with pKi of 8.5.
-
产品描述A potent, selective, orally active and CNS penetrant 5-HT6 receptor antagonist with pKi of 8.5, displays 1300-fold selectivity over other 13 5-HT receptor subtypes; inhibits 5-HT-stimulated cAMP accumulation in with pA2 of 7.63, enhances memory and learning following chronic administration in mice.
-
同义词SB 357134;SB357134
-
通路Endocrinology/Hormones
-
靶点5-HT Receptor
-
受体5-HT Receptor
-
研究领域——
-
适应症——
化学信息
-
CAS Number219963-52-7
-
分子量523.22
-
分子式C17H18Br2FN3O3S
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESO=S(C1=CC=C(OC)C(N2CCNCC2)=C1)(NC3=CC(Br)=CC(F)=C3Br)=O
-
化学全称N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-(piperazin-1-yl)benzene-1-sulfonamide
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Bromidge SM, et al. Bioorg Med Chem Lett. 2001 Jan 8;11(1):55-8.
2. Stean TO, et al. Pharmacol Biochem Behav. 2002 Apr;71(4):645-54.
3. Marcos B, et al. Eur J Neurosci. 2006 Sep;24(5):1299-306.
4. Rogers DC, et al. Psychopharmacology (Berl). 2001 Nov;158(2):114-9.
2. Stean TO, et al. Pharmacol Biochem Behav. 2002 Apr;71(4):645-54.
3. Marcos B, et al. Eur J Neurosci. 2006 Sep;24(5):1299-306.
4. Rogers DC, et al. Psychopharmacology (Berl). 2001 Nov;158(2):114-9.
产品手册
关联产品
-
Chlorpromazine hydro...
Chlorpromazine hydrochloride is a dopamine and potassium channel inhibitor used as the prototypical phenothiazine antipsychotic drug.
-
Clomipramine hydroch...
Clomipramine HCl is a serotonin transporter (SERT).
-
CART (62-76) (rat, h...
Cocaine- and amphetamine-regulated transcript (CART) peptide fragment that inhibits food intake. Attenuates NPY-induced feeding and decreases food intake in food-restricted goldfish, and induces anxiogenic-like effects in elevated plus-maze test in rats. Modulates the activity of striatal noradrenergic, and corticostrial and hypothalamic serotoninergic systems, with no major effect on dopaminergic pathways in rat brain.
