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Roquinimex
CAS No. 84088-42-6
Roquinimex ( FCF89 | FCF89 | LS 2616 | Linomide. US brand name: Linomide )
产品货号. M17607 CAS No. 84088-42-6
Roquinimex (Linomide) 是一种喹啉衍生物免疫刺激剂，可增加 NK 细胞活性和巨噬细胞细胞毒性；抑制血管生成并减少TNFα的分泌。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥300 | 有现货 |
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| 5MG | ￥478 | 有现货 |
|
| 10MG | ￥786 | 有现货 |
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| 25MG | ￥1426 | 有现货 |
|
| 50MG | ￥2406 | 有现货 |
|
| 100MG | ￥3864 | 有现货 |
|
| 200MG | ￥5532 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Roquinimex
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Roquinimex (Linomide) 是一种喹啉衍生物免疫刺激剂，可增加 NK 细胞活性和巨噬细胞细胞毒性；抑制血管生成并减少TNFα的分泌。
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产品描述Roquinimex, also known as LS 2616 and FCF89 (brande name: Linomide), is a quinoline-3-carboxamide with potential antineoplastic activity. Roquinimex inhibits endothelial cell proliferation, migration, and basement membrane invasion; reduces the secretion of the angiogenic factor tumor necrosis factor alpha by tumor-associated macrophages (TAMs); and inhibits angiogenesis. This agent is also an immune modulator that appears to alter cytokine profiles and enhance the activity of T cells, natural killer cells, and macrophages.
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体外实验——
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体内实验——
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同义词FCF89 | FCF89 | LS 2616 | Linomide. US brand name: Linomide
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通路Wnt/Notch/Hedgehog
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靶点Wnt/beta/catenin
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受体Others
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研究领域Inflammation/Immunology
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适应症——
化学信息
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CAS Number84088-42-6
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分子量308.34
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分子式C18H16N2O3
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纯度>98% (HPLC)
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溶解度DMSO : ≥ 83.3 mg/mL; 270.17 mM
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SMILESCN(c1ccccc1)C(=O)C3=C(O)c2ccccc2N(C)C3=O
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化学全称4-hydroxy-N,1-dimethyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Liu Q,etal. Roquinimex inhibits dextran sodium sulfate-induced murine colitis.Inflamm Res. 2003 Feb;52(2):64-8.
