Ridinilazole ( SMT19969 )

产品货号. M22106 CAS No. 308362-25-6

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产品名称

Ridinilazole
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Ridinilazole is a novel narrow-spectrum nonabsorbable antibiotic.
产品描述

Ridinilazole is a novel narrow-spectrum nonabsorbable antibiotic. Ridinilazole showed potent inhibition of C. difficile (MIC90=0.125 mg/L) and was markedly more active than either metronidazole (MIC90?=?8 mg/L) or vancomycin (MIC90?=?2 mg/L).ridinilazole , a novel antibacterial currently under development for the treatment of CDI.?Owing to its highly targeted spectrum of activity and ability to spare the normal gut microbiota, ridinilazole provides significant advantages over metronidazole and vancomycin, the mainstay antibiotics for CDI.?Ridinilazole is bactericidal against C. difficile and exhibits a prolonged post-antibiotic effect.?Furthermore, treatment with ridinilazole results in decreased toxin production.
同义词

SMT19969
通路

GPCR/G Protein
靶点

Antibacterial
受体

Antibacterial
研究领域

Immune system
适应症

Clostridium Difficile Infection

1.Vickers RJ, et al. Ridinilazole: a novel therapy for Clostridium difficile infection. Int J Antimicrob Agents. 2016 Aug;48(2):137-43.

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