ANY1 ( FosA inhibitor ANY1 )

产品货号. M14617 CAS No. 482574-02-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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产品名称

ANY1
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

ANY1 (FosA inhibitor ANY1) is a small molecule active site inhibitor of FosA (metal-dependent glutathione S-transferase) with IC50 of 5.1 uM (K. pneumoniae FosA).
产品描述

ANY1 (FosA inhibitor ANY1) is a small molecule active site inhibitor of FosA (metal-dependent glutathione S-transferase) with IC50 of 5.1 uM (K. pneumoniae FosA); binds to wild-type and mutant FosA3 measured by fluorescence quenching with Kd vales of 440-4880 nM; potentiates Fosfomycin (FOM) activity in representative Gram-negative pathogens.
同义词

FosA inhibitor ANY1
通路

GPCR/G Protein
靶点

Antibacterial
受体

Antibacterial
研究领域

——
适应症

——

CAS Number

482574-02-7
分子量

537.09
分子式

C15H7Br2N9O4
纯度

>98% (HPLC)
溶解度

——
SMILES

——
化学全称

3-bromo-6-[3-(3-bromo-2-oxo-1H-pyrazolo[1,5-a]pyrimidin-6-yl)-4-nitro-1H-pyrazol-5-yl]-1H-pyrazolo[1,5-a]pyrimidin-2-one

1. Tomich AD, et al. Antimicrob Agents Chemother. 2019 Jan 14. pii: AAC.01524-18.

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