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Relebactam

CAS No. 1174018-99-5

Relebactam ( MK-7655 )

产品货号. M10588 CAS No. 1174018-99-5

Relebactam (MK-7655)is a novel β-lactamase inhibitor that inhibited both class A and C β-lactamases in vitro.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥786 有现货
10MG ¥1256 有现货
25MG ¥2341 有现货
50MG ¥4358 有现货
100MG ¥6302 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Relebactam
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Relebactam (MK-7655)is a novel β-lactamase inhibitor that inhibited both class A and C β-lactamases in vitro.
  • 产品描述
    Relebactam (MK-7655)is a novel β-lactamase inhibitor that inhibited both class A and C β-lactamases in vitro; effectively restored imipenem's activity against imipenem-resistant Pseudomonas and Klebsiella strains at clinically achievable concentrations; reduces imipenem MICs for Enterobacteriaceae with KPC carbapenemases from 16-64 mg/L to 0.12-1 mg/L at a concentration of 4 mg/L.Bacterial Infection Phase 3 Clinical
  • 同义词
    MK-7655
  • 通路
    GPCR/G Protein
  • 靶点
    Antibacterial
  • 受体
    diazabicyclooctane
  • 研究领域
    Infection
  • 适应症
    Bacterial Infection

化学信息

  • CAS Number
    1174018-99-5
  • 分子量
    348.38
  • 分子式
    C12H20N4O6S
  • 纯度
    >98% (HPLC)
  • 溶解度
    10 mM in DMSO
  • SMILES
    O=S(O)(ON1[C@]2([H])CC[C@@H](C(NC3CCNCC3)=O)[N@@](C2)C1=O)=O
  • 化学全称
    Sulfuric acid, mono[(1R,2S,5R)-7-oxo-2-[(4-piperidinylamino)carbonyl]-1,6-diazabicyclo[3.2.1]oct-6-yl] ester

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Hirsch EB, et al. Antimicrob Agents Chemother. 2012 Jul;56(7):3753-7.
2. Blizzard TA, et al. Bioorg Med Chem Lett. 2014 Feb 1;24(3):780-5.
3. Livermore DM, et al. J Antimicrob Chemother. 2013 Oct;68(10):2286-90.
产品手册
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