021-51111890
购物车（0）
sales@molnova.cn
Rabeximod
CAS No. 872178-65-9
Rabeximod ( —— )
产品货号. M34686 CAS No. 872178-65-9
Rabeximod is a potent immunomodulator that reduces the severity of autoimmune diseases in rat models. Rabeximod inhibits arthritis in a time-dependent manner by stimulating TLR2 and TLR4 downstream to block the activation of inflammatory cells, most likely macrophages. Rabeximod effectively reduces brain antigen presentation in mice during anti-inflammatory therapy for traumatic brain injury.
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ￥3333 | 有现货 |
|
| 5MG | ￥5184 | 有现货 |
|
| 10MG | ￥7372 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称Rabeximod
-
注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
-
产品简述Rabeximod is a potent immunomodulator that reduces the severity of autoimmune diseases in rat models. Rabeximod inhibits arthritis in a time-dependent manner by stimulating TLR2 and TLR4 downstream to block the activation of inflammatory cells, most likely macrophages. Rabeximod effectively reduces brain antigen presentation in mice during anti-inflammatory therapy for traumatic brain injury.
-
产品描述Rabeximod is a potent immunomodulator that reduces the severity of autoimmune diseases in rat models. Rabeximod inhibits arthritis in a time-dependent manner by stimulating TLR2 and TLR4 downstream to block the activation of inflammatory cells, most likely macrophages. Rabeximod effectively reduces brain antigen presentation in mice during anti-inflammatory therapy for traumatic brain injury.
-
体外实验——
-
体内实验——
-
同义词——
-
通路Immunology/Inflammation
-
靶点TLR
-
受体TLR
-
研究领域——
-
适应症——
化学信息
-
CAS Number872178-65-9
-
分子量409.91
-
分子式C22H24ClN5O
-
纯度>98% (HPLC)
-
溶解度——
-
SMILESC(C(NCCN(C)C)=O)N1C=2C(C=3C1=CC=C(Cl)C3)=NC=4C(N2)=CC(C)=C(C)C4
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
产品手册
关联产品
-
Chloranil
Chloranil (tetrachloro-p-benzoquinone) triggers inflammation and neurological dysfunction through Toll-like receptor 4 signaling and can be used to model inflammation in mice.
-
Imiquimod hydrochlor...
Imiquimod hydrochloride (R 837 hydrochloride) 是一种选择性的 toll 样受体 7 (TLR7) 激动剂，作为一种免疫反应调节剂。Imiquimod hydrochloride 在体内表现出抗病毒和抗肿瘤作用。Imiquimod hydrochloride 可用于外生殖器、肛周疣、癌症和 COVID-19 的研究。
-
CU CPT 4a
CU CPT 4a 是一种选择性 TLR3 抑制剂（IC50：在 RAW 264.7 细胞中为 3.44 μM）。
