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RO8191

CAS No. 691868-88-9

RO8191 ( CDM-3008; RO4948191 )

产品货号. M27515 CAS No. 691868-88-9

RO8191 (CDM-3008), an imidazonaphthyridine compound, is an agonist of interferon (IFN) receptor.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥429 有现货
5MG ¥721 有现货
10MG ¥1191 有现货
25MG ¥2608 有现货
50MG ¥4155 有现货
100MG ¥6051 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    RO8191
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    RO8191 (CDM-3008), an imidazonaphthyridine compound, is an agonist of interferon (IFN) receptor.
  • 产品描述
    RO8191 (CDM-3008), an imidazonaphthyridine compound, is an agonist of interferon (IFN) receptor.(In Vitro):RO8191 strongly suppresses HCV replicon activity at 72 h in a dose-dependent manner. RO8191 reduces levels of the proteins HCV NS3 and NS4A, which are localized mainly in the perinuclear region of the replicon cells.(In Vivo):RO8191 significantly induces antiviral genes Oas1b, Mx1, and Pkr in the livers of six-week-old C57BL/6J mice.
  • 同义词
    CDM-3008; RO4948191
  • 通路
    Microbiology/Virology
  • 靶点
    HCV
  • 受体
    thyrotropin receptor (TSHR)
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    691868-88-9
  • 分子量
    373.2
  • 分子式
    C14H5F6N5O
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    FC(F)(F)c1cc(c2ccc3nc(cn3c2n1)-c1nnco1)C(F)(F)F
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Neumann S, et al. A new small-molecule antagonist inhibits Graves' disease antibody activation of the TSH receptor. J Clin Endocrinol Metab. 2011 Feb;96(2):548-54.
产品手册
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