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R-7050

CAS No. 303997-35-5

R-7050 ( R-7050; R 7050; R7050; TNF-α Antagonist III )

产品货号. M18394 CAS No. 303997-35-5

R-7050 is a tumor necrosis factor receptor (TNFR) antagonist with greater selectivity toward TNFα.

纯度: 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
2MG ¥308 有现货
5MG ¥494 有现货
10MG ¥786 有现货
25MG ¥1758 有现货
50MG ¥2406 有现货
100MG ¥3953 有现货
500MG ¥8586 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    R-7050
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    R-7050 is a tumor necrosis factor receptor (TNFR) antagonist with greater selectivity toward TNFα.
  • 产品描述
    R-7050 is a TNF-α receptor antagonist. It acts by blocking receptor-adaptor molecule complex formation and subsequent receptor internalization, but not TNF-α ligand-receptor binding.
  • 同义词
    R-7050; R 7050; R7050; TNF-α Antagonist III
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    TNF-α
  • 研究领域
    Cancer
  • 适应症
    ——

化学信息

  • CAS Number
    303997-35-5
  • 分子量
    380.77
  • 分子式
    C16H8ClF3N4S
  • 纯度
    98%
  • 溶解度
    DMSO : 25 mg/mL 65.66 mM;
  • SMILES
    FC(F)(F)c3nnc2c(nc1ccc(Cl)cc1n23)Sc4ccccc4
  • 化学全称
    8-Chloro-4-(phenylthio)-1-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Gururaja TL, et al. A class of small molecules that inhibit TNFalpha-induced survival and death pathways viaprevention of interactions between TNFalphaRI, TRADD, and RIP1. Chem Biol. 2007 Oct;14(10):1105-18.
产品手册
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