• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

Homo-VK-II-36

CAS No. 1479049-35-8

Homo-VK-II-36 ( Homo VK II 36; HomoVKII36; Homo-V-II-36 )

产品货号. M23634 CAS No. 1479049-35-8

Homo-VK-II-36 is a carvedilol analogue that acts by inhibiting store-?overload-induced calcium release through the RyR2 channel.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥1596 有现货
10MG ¥2535 有现货
25MG ¥4317 有现货
50MG ¥6221 有现货
100MG ¥8748 有现货
200MG 获取报价 有现货
500MG 获取报价 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Homo-VK-II-36
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Homo-VK-II-36 is a carvedilol analogue that acts by inhibiting store-?overload-induced calcium release through the RyR2 channel.
  • 产品描述
    Homo-VK-II-36 is a carvedilol analogue that acts by inhibiting store-?overload-induced calcium release through the RyR2 channel.
  • 同义词
    Homo VK II 36; HomoVKII36; Homo-V-II-36
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    RyR2 channel
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    1479049-35-8
  • 分子量
    460.5
  • 分子式
    C27H28N2O5
  • 纯度
    >98% (HPLC)
  • 溶解度
    DMSO:10 mM
  • SMILES
    COC1=CC=CC=C1OCCN2CC(OCC2=O)CCOC3=CC=CC4=C3C5=CC=CC=C5N4
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Zhang JZ, McLay JC, Jones PP. The arrhythmogenic human HRC point mutation S96A leads to spontaneous Ca(2+) release due to an impaired ability to buffer store Ca(2+). J Mol Cell Cardiol. 2014 Sep;74:22-31. doi: 10.1016/j.yjmcc.2014.04.019. Epub 2014 May 5. PubMed PMID: 24805197.
产品手册
关联产品
  • Quercetin 3,7-digluc...

    Quercetin 3,7-diglucoside exhibits antioxidant activity.

  • ML221

    ML221 is a potentapelin /APJfunctional antagonist, inhibiting apelin-13-mediated activation of APJ, withIC50s of 0.70 μM in the cAMP assay, and 1.75 μM in the β-arrestin assay, andEC80of 10 nM in both assays.

  • Conduritol A

    Conduritol A has a hypoglycemic effect, can have an effect on regulating the metabolism of blood lipid, free-radical scavenging, enhancing the antioxidant ability, potentiating immune function; it also can markedly prevent the diabetic rats from getting cataracts through the inhibition of lens aldose reductase.