R-1479 ( R 1479;4'-Azidocytidine;R1479 )

产品货号. M14594 CAS No. 478182-28-4

A potent, specific inhibitor of HCV NS5B polymerase and HCV replication (IC50=1.28 uM, replicon assay).

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
2MG	￥1596	有现货
5MG	￥2811	有现货
10MG	￥4026	有现货
25MG	￥6423	有现货
50MG	￥9153	有现货
100MG	￥12312	有现货
200MG	获取报价	有现货
500MG	获取报价	有现货
1G	获取报价	有现货

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生物学信息

产品名称

R-1479
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

A potent, specific inhibitor of HCV NS5B polymerase and HCV replication (IC50=1.28 uM, replicon assay).
产品描述

A potent, specific inhibitor of HCV NS5B polymerase and HCV replication (IC50=1.28 uM, replicon assay); shows no effect on cell viability or proliferation of HCV replicon or Huh-7 cells at >2 mM; inhibits RNA synthesis mediated by NS5B with IC50 of 320 nM, is the active form of Balapiravir (R-1479).
同义词

R 1479;4'-Azidocytidine;R1479
通路

Microbiology/Virology
靶点

HCV
受体

HCV
研究领域

Infection
适应症

——

化学信息

CAS Number

478182-28-4
分子量

284.23
分子式

C9H12N6O5
纯度

>98% (HPLC)
溶解度

DMSO
SMILES

NC1=NC(N([C@@H]2O[C@@](N=[N+]=[N-])([C@H]([C@H]2O)O)CO)C=C1)=O
化学全称

Cytidine, 4'-C-azido-

运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1. Smith DB, et al. Bioorg Med Chem Lett. 2007 May 1;17(9):2570-6.
2. Klumpp K, et al. J Biol Chem. 2006 Feb 17;281(7):3793-9.
3. Ali S, et al. Antimicrob Agents Chemother. 2008 Dec;52(12):4356-69.

计算器

浓度计算器

摩尔计算器

分子量计算器

产品手册

关联产品

R-7128

The prodrug of PSI-6130, a potent, specific inhibitor of HCV RNA synthesis by inhibiting the NS5B RNA polymerase.
Glecaprevir

Glecaprevir (ABT 493;A 1282576) is a novel HCV NS3/4A protease inhibitor with pan-genotypic activity, inhibits NS3/4A proteases from HCV genotypes 1-6 in vitro with IC50 of 3.5-11.3 nM.
Balapiravir

The prodrug of R1479, a potent, specific and oral HCV NS5B polymerase inhibitor.

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